SCHEMBL28030165

SCHEMBL28030165

CCCCCCl.COc1ccc(CSOSCc2ccc(OC)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
IDO1 P14902 3/20 0.41
APP P05067 1/20 0.40
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
MMP2 P08253 2/20 0.39
MMP9 P14780 2/20 0.39
MMP8 P22894 2/20 0.39
MMP13 P45452 2/20 0.39
TSHR P16473 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28030164 0.87 CASP3 (0.46) CASP3SENP8SENP7SENP6IDO1
SCHEMBL190895 0.83 IDO1 (0.55) IDO1APPBCHEACHETSHR
SCHEMBL28854032 0.82 ALDH1A1 (0.40) TSHRSMN1; SMN2ALDH1A1TP53KMT2A
Hydrochloric Acid SCHEMBL5797808 0.81 IDO1 (0.56) IDO1APPBCHEACHETSHR
Estragole SCHEMBL27944888 0.78 ALDH1A1 (0.69) CASP3SENP8SENP7SENP6MMP2
Anisole SCHEMBL27647858 0.74 CA4 (0.56) CASP3SENP8SENP7SENP6TSHR
SCHEMBL28784936 0.74 ALDH1A1 (0.39) TSHRSMN1; SMN2ALDH1A1TP53KMT2A
Anisole SCHEMBL28132051 0.73 CA4 (0.54) CASP3SENP8SENP7SENP6TSHR
SCHEMBL27958966 0.72 LMNA (0.46) CASP3SENP8SENP7SENP6IDO1
SCHEMBL5252007 0.72 CALM1 (0.60) CASP3SENP8SENP7SENP6IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102558001-B Manufacture the modification method of hydrazides WYETH LLC (US) 2015-09-23 CN disclosed