SCHEMBL28030407

SCHEMBL28030407

O=C(c1ccccc1)c1cc(-c2ccccc2)c(O)c(-c2ccccc2)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
PTPN1 P18031 3/20 0.47
PTPN2 P17706 1/20 0.47
PTPN6 P29350 1/20 0.47
BCL2 P10415 1/20 0.46
MCL1 Q07820 1/20 0.46
HNF4A P41235 1/20 0.46
AKR1C3 P42330 2/20 0.45
AKR1C2 P52895 1/20 0.45
AKR1C1 Q04828 1/20 0.45
CYP2C8 P10632 1/20 0.45
CYP2C9 P11712 1/20 0.45
MEN1 O00255 1/20 0.45
USP2 O75604 1/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45
KEAP1 Q14145 1/20 0.45
NFE2L2 Q16236 1/20 0.45
PDE4A P27815 1/20 0.44
ADORA1 P30542 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29791322 0.82 PDE4B (0.55) ALDH1A1BCL2MCL1PDE4A
SCHEMBL31000063 0.80 MEN1 (0.54) ALDH1A1PTPN1PTPN2PTPN6HNF4A
SCHEMBL10978801 0.80 MEN1 (0.54) ALDH1A1PTPN1PTPN2PTPN6HNF4A
SCHEMBL5491735 0.80 ALDH1A1 (0.63) ALDH1A1AKR1C3CYP2C8CYP2C9MEN1
SCHEMBL27449650 0.79 ALDH1A1 (0.54) ALDH1A1AKR1C3CYP2C8CYP2C9MEN1
SCHEMBL27839362 0.79 PTPN1 (0.50) ALDH1A1PTPN1PTPN2PTPN6BCL2
SCHEMBL1666495 0.78 ALDH1A1 (0.53) ALDH1A1AKR1C3CYP2C8CYP2C9MEN1
SCHEMBL4326249 0.78 BACE1 (0.56) ALDH1A1PTPN1PTPN2PTPN6HNF4A
SCHEMBL6034374 0.77 HNF4A (0.70) ALDH1A1PTPN1PTPN2PTPN6BCL2
SCHEMBL8003100 0.77 ALDH1A1 (0.56) ALDH1A1PTPN1PTPN2PTPN6AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105238271-A Smoke-suppression non-cured rubber bitumen waterproof coating material TIANCHANG JINNIU WATERPROOF ANTI CORROSION MATERIAL CO LTD 2016-01-13 CN disclosed