Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 7/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250756 | 0.88 | CNR1 (0.53) | ALDH1A1MEN1RAB9AKMT2ALMNA | |
| SCHEMBL10726242 | 0.88 | CNR2 (0.50) | ALDH1A1GABRA1GABRB1MEN1RAB9A | |
| SCHEMBL29279320 | 0.83 | PTPN1 (0.58) | ALDH1A1TDP1LMNAMAPTPTPN1 | |
| SCHEMBL9455582 | 0.82 | CDC25B (0.61) | ALDH1A1ATMKMT2APTPN1AKR1C3 | |
| SCHEMBL8145249 | 0.80 | PTPN1 (0.50) | ALDH1A1PTPN1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6421185 | 0.80 | ATM (0.59) | ALDH1A1ATMTDP1L3MBTL1MEN1 | |
| SCHEMBL29022930 | 0.80 | MAPT (0.55) | LMNAMAPTPTPN1AKR1C3AKR1C2 | |
| SCHEMBL3349765 | 0.78 | ATM (0.84) | ALDH1A1ATMTDP1L3MBTL1GABRA1 | |
| Benzophenone SCHEMBL260937 | 0.78 | ALDH1A1 (0.82) | ALDH1A1ATMTDP1L3MBTL1MEN1 | |
| SCHEMBL133982 | 0.78 | ATM (0.84) | ALDH1A1ATMTDP1L3MBTL1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063815-A | TREATMENT OF METABOLIC DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-16 | — | — | US | disclosed |