Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | IAPP | P10997 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846204 | 0.84 | FFAR1 (0.61) | FFAR1FFAR4TPMTNPSR1 | |
| SCHEMBL9632300 | 0.84 | ALDH1A1 (0.54) | KMT2AFFAR1IAPPFFAR4TPMT | |
| SCHEMBL4910633 | 0.82 | PGK1 (0.48) | KMT2AFFAR1IAPPTDP1L3MBTL1 | |
| SCHEMBL5846491 | 0.82 | FFAR1 (0.42) | KMT2AFFAR1TDP1L3MBTL1FFAR4 | |
| SCHEMBL27964907 | 0.82 | CAPN1 (0.46) | KMT2AFFAR1FFAR4TPMTPGK1 | |
| SCHEMBL11392001 | 0.79 | GPR17 (0.42) | KMT2AIAPPTDP1L3MBTL1ALOX5 | |
| SCHEMBL9861207 | 0.79 | KMT2A (0.49) | KMT2AFFAR1FFAR4HDAC8CNR1 | |
| SCHEMBL7337631 | 0.79 | TAAR1 (0.57) | KMT2AFFAR1TDP1L3MBTL1FFAR4 | |
| SCHEMBL27986450 | 0.78 | KMT2A (0.43) | KMT2AFFAR1TDP1ALOX5FFAR4 | |
| SCHEMBL28135123 | 0.77 | IAPP (0.42) | KMT2AFFAR1IAPPTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863140-A | 3- oxo -2,6- diphenyl -2,3- dihydrogen dazin -4- formamide | 拜耳医药股份有限公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-108368102-A | 2- amino -1,3,4- thiadiazines and antifungal agent based on 2- amino -1,3,4- oxadiazines | F2G有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-105164113-A | Pyrroloamide inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | disclosed |
| CN-102482284-B | Pyrazolopyrimidine compounds and methods as JAK inhibitors | GENENTECH, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-104910161-A | Pyrazolopyrimidine JAK inhibitor compounds and methods | GENENTECH INC | 2015-09-16 | — | — | CN | disclosed |
| CN-102341379-B | Benzothiazine derivative, its preparation method and the application as medicine thereof | PIERRE FABRE MEDICAMENT (FR) | 2015-08-26 | — | — | CN | disclosed |