Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 4/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29001876 | 0.84 | AOC3 (0.60) | AOC3CNR2CNR1ALDH1A1GFER | |
| SCHEMBL17115661 | 0.82 | AOC3 (0.58) | AOC3CNR2CNR1ALDH1A1GFER | |
| SCHEMBL3729424 | 0.82 | AOC3 (0.58) | AOC3CA2CNR2CNR1ALDH1A1 | |
| SCHEMBL22504113 | 0.81 | AOC3 (0.58) | AOC3CNR2CNR1ALDH1A1GFER | |
| SCHEMBL3658844 | 0.80 | CA2 (0.57) | CA2ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL16009282 | 0.79 | ALDH1A1 (0.51) | AOC3CA2CNR2ALDH1A1CYP3A4 | |
| SCHEMBL11290860 | 0.78 | CA2 (0.80) | CA2ALDH1A1KDM4E | |
| SCHEMBL14839588 | 0.78 | CYP3A4 (0.58) | CA2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL2702012 | 0.77 | CA2 (0.64) | CA2ALDH1A1 | |
| SCHEMBL11077525 | 0.77 | CYP4Z1 (0.54) | AOC3CNR2CNR1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104936954-A | compounds and methods of use thereof | AGIOS PHARMACEUTICALS INC | 2015-09-23 | — | — | CN | disclosed |