Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341527 | 0.84 | THRA (0.52) | ALDH1A1CYP3A4THRATHRBCRHBP | |
| SCHEMBL11341529 | 0.84 | THRA (0.52) | ALDH1A1CYP3A4THRATHRBCRHBP | |
| SCHEMBL11519243 | 0.83 | ALDH1A1 (0.51) | ALDH1A1CYP3A4THRATHRBCRHBP | |
| SCHEMBL28031258 | 0.83 | HDAC1 (0.50) | ALDH1A1KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL15709977 | 0.81 | SLC7A5 (0.50) | ALDH1A1CYP3A4THRATHRBCNR2 | |
| SCHEMBL28030690 | 0.79 | AOC3 (0.61) | ALDH1A1CYP3A4CNR2KDM4EMAPK1 | |
| SCHEMBL10339219 | 0.78 | CA2 (0.54) | ALDH1A1KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL3510031 | 0.77 | ALDH1A1 (0.55) | ALDH1A1CYP3A4THRATHRBCNR2 | |
| SCHEMBL7770956 | 0.77 | LMNA (0.46) | ALDH1A1CYP3A4KDM4ELMNAPOLB | |
| SCHEMBL7672430 | 0.77 | ALDH1A1 (0.60) | ALDH1A1CYP3A4THRATHRBCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9791609-B2 | Polarization film and display device | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-10-17 | — | — | US | disclosed |
| CN-104936954-A | compounds and methods of use thereof | AGIOS PHARMACEUTICALS INC | 2015-09-23 | — | — | CN | disclosed |
| US-20140254012-A1 | POLARIZATION FILM AND DISPLAY DEVICE | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2014-09-11 | — | — | US | disclosed |