SCHEMBL28030823

SCHEMBL28030823

CC(C)C1=Cc2c(cccc2-c2ccccc2)[CH]1.Cl[Hf]Cl

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 2/20 0.32
CDC25B P30305 2/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4457465 0.94 CDC25B (0.35) CDC25ACDC25BCYP2A6
SCHEMBL27757699 0.92 CDC25A (0.34) CDC25ACDC25BCYP2A6
SCHEMBL27495777 0.91 CDC25A (0.32) CDC25ACDC25BCYP2A6
SCHEMBL15603402 0.88 CDC25A (0.33) CDC25ACDC25B
SCHEMBL1241787 0.85 CDC25A (0.32) CDC25ACDC25B
SCHEMBL28210709 0.85 PTAFR (0.33)
SCHEMBL15163555 0.81 MEN1 (0.36) CDC25ACDC25B
SCHEMBL27706881 0.81 ADORA3 (0.34) CDC25ACDC25B
SCHEMBL27670349 0.81 ADORA3 (0.32)
SCHEMBL28034435 0.81 HSD11B1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105026408-A Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORP 2015-11-04 CN disclosed
CN-105008408-A METHOD FOR PRODUCING ETHYLENE/[alpha]-OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP 2015-10-28 CN disclosed