SCHEMBL28210709

SCHEMBL28210709

CC(C)C1=Cc2c(cccc2-c2ccc(C(C)(C)C)cc2)[CH]1.Cl[Hf]Cl

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 1/20 0.33
S1PR1 P21453 1/20 0.32
BRD4 O60885 1/20 0.30
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673246 0.95 PTAFR (0.35) PTAFRS1PR1BRD4CREBBP
SCHEMBL27613148 0.93 PTAFR (0.34) PTAFRS1PR1BRD4CREBBP
SCHEMBL27512767 0.92 PTAFR (0.33) PTAFRBRD4CREBBP
SCHEMBL28030823 0.85 CDC25A (0.32)
SCHEMBL28857412 0.83 AKR1C3 (0.37) PTAFRBRD4CREBBP
SCHEMBL1238964 0.82 RXRA (0.33) PTAFR
SCHEMBL28769778 0.82 KIF11 (0.36)
SCHEMBL27670367 0.82 KIF11 (0.33)
SCHEMBL4463931 0.82 PTAFR (0.33) PTAFRBRD4CREBBP
SCHEMBL15163648 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114599661-B Transition metal compound, method for preparing the same, and catalyst composition comprising the same 株式会社LG化学 2024-03-12 CN disclosed
CN-114599661-A Transition metal compound, method for preparing the same, and catalyst composition comprising the same 株式会社LG化学 2022-06-07 CN disclosed
CN-107921424-A ALUMINUM ALKYLS WITH PENDANT OLEFINS ON CLAYS 埃克森美孚化学专利公司 2018-04-17 CN disclosed