SCHEMBL3962887

SCHEMBL3962887

O=C1COc2ccccc2C1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.54
MAOA P21397 3/20 0.50
MAOB P27338 3/20 0.50
CYP2A6 P11509 1/20 0.46
OXTR P30559 1/20 0.42
PKM P14618 1/20 0.39
TSHR P16473 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.39
ITGB2 P05107 1/20 0.39
ICAM1 P05362 1/20 0.39
ITGAL P20701 1/20 0.39
DAPK3 O43293 1/20 0.37
RET P07949 1/20 0.37
PRKACA P17612 1/20 0.37
GRK5 P34947 1/20 0.37
CDK8 P49336 1/20 0.37
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
CDK5 Q00535 1/20 0.37
PRKCQ Q04759 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30450885 1.00 CYP1A2 (0.54) CYP1A2MAOAMAOBCYP2A6OXTR
SCHEMBL30169745 0.81 CYP1A2 (0.48) CYP1A2MAOAMAOBCYP2A6OXTR
SCHEMBL987924 0.81 CYP2A6 (0.52) CYP1A2MAOAMAOBCYP2A6OXTR
Benzothiophene SCHEMBL27780599 0.80 CYP1A2 (0.36) CYP1A2MAOAMAOBCYP2A6OXTR
SCHEMBL868520 0.80 ABCG2 (0.52) CYP1A2MAOAMAOBOXTRPKM
SCHEMBL6108899 0.80 CYP2A6 (0.50) CYP1A2MAOAMAOBCYP2A6OXTR
SCHEMBL10462577 0.79 MAOA (0.73) CYP1A2MAOAMAOBCYP2A6RAB9A
SCHEMBL10460744 0.77 PKM (0.48) MAOAMAOBPKMTSHRRAB9A
SCHEMBL489968 0.76 MAOA (0.61) CYP1A2MAOAMAOBOXTRTSHR
SCHEMBL10170816 0.75 OXTR (0.52) MAOAMAOBOXTRABCG2ITGB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114450088-A Composition and method for regenerating cation exchange resins 泰格鲁斯有限责任公司 2022-05-06 CN claimed
CN-114007745-A System and apparatus for conditioning water and regenerating ion exchange resins 泰格鲁斯有限责任公司 2022-02-01 CN claimed
CN-112898260-A 3-carbonyl-2H-benzopyran compound or pharmaceutically acceptable salt thereof, preparation method and application 中国药科大学 2021-06-04 CN claimed
EP-0421829-A1 Benzopyranone-beta-D-thioxylosides, method for their preparation and their use FOURNIER INDUSTRIE ET SANTE (FR) 1991-04-10 EP claimed
US-4721787-A CONDENSATION, REDUCTION, DEHYDRATION CIBA-GEIGY CORPORATION (US) 1988-01-26 US claimed
US-12358887-B2 IKAROS Zinc Finger Family degraders and uses thereof GILEAD SCIENCES, INC. (US) 2025-07-15 US disclosed
EP-4464703-A2 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF Gilead Sciences, Inc. (US) 2024-11-20 EP disclosed
WO-2024221478-A1 METHOD FOR DETERMINING TOTAL AMOUNT OF SOY ISOFLAVONES IN FOOD 江南大学 2024-10-31 WO disclosed
EP-4245756-B1 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF GILEAD SCIENCES INC (US) 2024-10-09 EP disclosed
CN-118666820-A Tulip essence A-oxindole-chromone spliced compound and preparation method and application thereof 咸阳师范学院 2024-09-20 CN disclosed
CN-118638127-A Double spiro [ pyrrolinone-oxindole-hexahydroshanone ] spliced compound and preparation method and application thereof 咸阳师范学院 2024-09-13 CN disclosed
CN-116135848-B Coumarin compound and preparation method and application thereof 中国科学院兰州化学物理研究所 2024-03-12 CN disclosed
EP-0421829-A1 Benzopyranone-beta-D-thioxylosides, method for their preparation and their use FOURNIER INDUSTRIE ET SANTE (FR) 1991-04-10 EP disclosed
EP-0421829-A1 Benzopyranone-beta-D-thioxylosides, method for their preparation and their use FOURNIER INDUSTRIE ET SANTE (FR) 1991-04-10 EP disclosed
US-4802911-A HERBICIDES, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-07 US disclosed
US-4721787-A CONDENSATION, REDUCTION, DEHYDRATION CIBA-GEIGY CORPORATION (US) 1988-01-26 US disclosed
US-4721787-A CONDENSATION, REDUCTION, DEHYDRATION CIBA-GEIGY CORPORATION (US) 1988-01-26 US disclosed
US-4604397-A Certain benzo-(pyrano and thiopyrano)-pyridines, useful as CNS agents CIBA-GEIGY CORPORATION (US) 1986-08-05 US disclosed
EP-0161218-A2 Benzo-(pyrano and thiopyrano)pyridines CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed
US-4381120-A Desensitization system for carbonless copy paper CHAMPION INTERNATIONAL CORPORATION (US) 1983-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358887-B2 IKAROS Zinc Finger Family degraders and uses thereof IKZF2, IKZF1, IKZF3 CYP1A2 2296/4885MAOA 3027/4885MAOB 2885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.