SCHEMBL28031086

SCHEMBL28031086

CCC(F)c1ccccc1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNQ2 O43526 1/20 0.37
MAPT P10636 1/20 0.37
DPP4 P27487 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
BCL2L1 Q07817 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAPK1 P28482 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
ADRB2 P07550 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5790615 0.85 ALDH1A1 (0.37) KCNQ2MAPTDPP4PDCD1CD274
SCHEMBL27669214 0.81 GPR84 (0.41) KCNQ2MAPTDPP4PDCD1CD274
SCHEMBL8679017 0.79 ADORA3 (0.41) KCNQ2MAPTDPP4PDCD1CD274
SCHEMBL1442681 0.79 SOAT1 (0.41)
SCHEMBL5551237 0.78 TSHR (0.55) KCNQ2MAPTDPP4PDCD1CD274
SCHEMBL9620498 0.77 CA12 (0.42) MAPTDPP4PDCD1CD274ALDH1A1
SCHEMBL31432929 0.76 TRPA1 (0.46) MAPTDPP4ALDH1A1HSD17B10HPGD
SCHEMBL4873147 0.76 TRPA1 (0.46) MAPTDPP4ALDH1A1HSD17B10HPGD
SCHEMBL10449366 0.76 DPP4 (0.41) KCNQ2MAPTDPP4PDCD1CD274
Ethane SCHEMBL5663955 0.76 TSHR (0.53) KCNQ2MAPTDPP4PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104945421-A Copper perfluorocarboxylate (I) reagent, and preparation method and application thereof UNIV FUZHOU 2015-09-30 CN disclosed