Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4545204 | 0.77 | DYRK1A (0.56) | ERN1DYRK1AKCNH2HRH3ACMSD | |
| SCHEMBL28031963 | 0.76 | CA2 (0.47) | DYRK1ACDK9NFKB1MAOAMAOB | |
| SCHEMBL26260192 | 0.74 | BACE1 (0.61) | ERN1BACE1DYRK1AKCNH2PDGFRB | |
| SCHEMBL28151739 | 0.73 | ENPP3 (0.43) | DYRK1ACDK9MAP4K4CLK4MAOA | |
| SCHEMBL28031959 | 0.73 | CA2 (0.42) | DYRK1ACDK9NFKB1MAOAMAOB | |
| SCHEMBL28822331 | 0.73 | DYRK1A (0.41) | DYRK1ACDK9CYP2A6NFKB1MAOA | |
| SCHEMBL28031961 | 0.73 | DYRK1A (0.41) | DYRK1ACDK9NFKB1MAOAMAOB | |
| SCHEMBL26260215 | 0.72 | BACE1 (0.59) | ERN1BACE1DYRK1AKCNH2NQO2 | |
| SCHEMBL17086905 | 0.70 | MAOA (0.48) | DYRK1ACDK9PIM1CYP2A6NFKB1 | |
| SCHEMBL7629662 | 0.70 | ERN1 (0.67) | ERN1BACE1KCNH2NQO2CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061372-B | A kind of synthetic method of aphthofurans class compound | 湖南大学 | 2017-06-20 | — | — | CN | disclosed |
| CN-105061372-A | Synthetic methods of naphthopyran compounds | UNIV HUNAN | 2015-11-18 | — | — | CN | disclosed |