SCHEMBL28031388

SCHEMBL28031388

CC(C)c1ccc(-c2cccc3c2C=C[CH]3)cc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36
BRD4 O60885 1/20 0.35
CREBBP Q92793 1/20 0.35
DGAT1 O75907 1/20 0.33
RAB9A P51151 2/20 0.30
PAX8 Q06710 1/20 0.30
NOD2 Q9HC29 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
NOTUM Q6P988 1/20 0.30
PTPN5 P54829 1/20 0.30
ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28041349 0.94 MEN1 (0.33) MAPTMEN1USP2LMNAKMT2A
SCHEMBL1643834 0.85 RXRA (0.30)
SCHEMBL28031401 0.84 RXRA (0.39) MAPTBRD4CREBBPL3MBTL1TP53
SCHEMBL28031409 0.81 PTGS2 (0.40) MEN1KMT2ARAB9ANPC1TP53
SCHEMBL6650232 0.79 PTGS2 (0.36) MAPTMEN1LMNAKMT2ARAB9A
SCHEMBL26190 0.78 ALDH1A1 (0.37)
SCHEMBL28031393 0.77 PTGS2 (0.40)
SCHEMBL28030817 0.77 ALDH1A1 (0.35) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL27463443 0.77 ALDH1A1 (0.35)
SCHEMBL28150039 0.77 ABL1 (0.46) MAPTLMNARAB9ANPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105008408-B METHOD FOR PRODUCING ETHYLENE/[alpha]-OLEFIN COPOLYMER 日本聚乙烯株式会社 2017-05-10 CN disclosed
CN-105026408-A Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORP 2015-11-04 CN disclosed
CN-105008408-A METHOD FOR PRODUCING ETHYLENE/[alpha]-OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP 2015-10-28 CN disclosed