Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117187 | 0.81 | CD74 (0.40) | CNR2HTR6CYP11B1CYP11B2KDM4E | |
| SCHEMBL694560 | 0.80 | TNF (0.44) | HTR6LMNATNFCYP11B1CYP11B2 | |
| SCHEMBL2117424 | 0.78 | HTR6 (0.48) | HTR6PLA2G2ALMNAALDH1A1 | |
| SCHEMBL27731250 | 0.76 | ICMT (0.51) | HTR6LMNA | |
| SCHEMBL3856954 | 0.76 | AGXT (0.43) | HTR6LMNA | |
| SCHEMBL27731265 | 0.76 | SERPINE1 (0.43) | HTR6 | |
| SCHEMBL28030916 | 0.76 | PKM (0.46) | CNR1ACHECNR2PLA2G2ALMNA | |
| SCHEMBL27751725 | 0.76 | HDAC8 (0.40) | SLC2A1LMNACYP11B1CYP11B2KDM4E | |
| SCHEMBL27731268 | 0.76 | ICMT (0.52) | LMNA | |
| SCHEMBL27751707 | 0.74 | MAPT (0.45) | CNR2LMNAMAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870422-B | Amine derivative or its salt | 富士胶片富山化学株式会社 | 2019-03-15 | — | — | CN | disclosed |
| CN-104870422-A | Novel amine derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |