Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.57 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
| ▸ | JAK3 | P52333 | 2/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228891 | 0.85 | ALK (0.49) | ALKBCAT2JAK2JAK3PTK2 | |
| SCHEMBL6264332 | 0.80 | FABP4 (0.70) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL20766620 | 0.80 | CA2 (0.62) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL5680858 | 0.80 | FABP4 (0.51) | ALKFABP4TTRCCNA2CDK2 | |
| Ammonia Solution, Strong SCHEMBL1556275 | 0.78 | NR4A1 (0.71) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL1855312 | 0.77 | JAK2 (0.49) | ALKBCAT2JAK2JAK3PTK2 | |
| SCHEMBL2634765 | 0.77 | HTR6 (0.62) | ALKBCAT2JAK2JAK3PTK2 | |
| SCHEMBL27792302 | 0.76 | PTGS1 (0.68) | FABP4PTK2MAPTKDM4EGAA | |
| SCHEMBL14215794 | 0.76 | FABP4 (0.47) | ALKFABP4TTRCCNA2CDK2 | |
| SCHEMBL14632174 | 0.76 | FABP4 (0.47) | ALKBCAT2FABP4TTRCCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105026403-A | Tetracyclic bromodomain inhibitors | ABBVIE INC | 2015-11-04 | — | — | CN | disclosed |