Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463347 | 0.81 | MAPT (0.53) | MAPTNPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL428217 | 0.76 | ALDH1A1 (0.56) | MAPTNPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL28873228 | 0.76 | CYP2A6 (0.42) | NPC1RAB9AALDH1A1MEN1LMNA | |
| SCHEMBL27975003 | 0.76 | MAPT (0.42) | MAPTRAB9AALDH1A1ALOX12TDP1 | |
| SCHEMBL3079091 | 0.76 | MAPT (0.44) | MAPTNPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL1485943 | 0.76 | TGM2 (0.48) | MAPTNPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL360732 | 0.74 | — | — | |
| SCHEMBL17539252 | 0.74 | MEN1 (0.44) | MAPTNPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL10889869 | 0.74 | ALDH1A1 (0.54) | MAPTNPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL9550177 | 0.72 | MAPT (0.50) | MAPTNPC1RAB9AALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017036-A | 2-(arylamino ethyl amino) benzyl alcohol compound with antimicrobial activity and applications thereof | UNIV HUNAN SCI & TECHNOLOGY | 2015-11-04 | — | — | CN | disclosed |