SCHEMBL428217

SCHEMBL428217

Cc1ccc(NC=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
LMNA P02545 2/20 0.50
MAPT P10636 4/20 0.48
NPC1 O15118 4/20 0.48
RAB9A P51151 3/20 0.48
ALOX12 P18054 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP2A6 P11509 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
DHODH Q02127 1/20 0.44
TGM2 P21980 1/20 0.43
KDM4E B2RXH2 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
POLB P06746 1/20 0.43
HPGD P15428 2/20 0.42
ACHE P22303 1/20 0.42
NMT1 P30419 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10889869 0.97 ALDH1A1 (0.54) ALDH1A1LMNAMAPTNPC1RAB9A
SCHEMBL2321992 0.93 ALDH1A1 (0.50) ALDH1A1LMNAMAPTNPC1RAB9A
SCHEMBL14403087 0.87 ALDH1A1 (0.45) ALDH1A1LMNAMAPTNPC1RAB9A
SCHEMBL14402927 0.87 TEAD4 (0.47) ALDH1A1LMNAMAPTNPC1RAB9A
SCHEMBL469386 0.86 ALDH1A1 (0.72) ALDH1A1LMNAMAPTNPC1RAB9A
SCHEMBL21376809 0.82 ALDH1A1 (0.41) ALDH1A1LMNAMAPTNPC1RAB9A
SCHEMBL13790230 0.81 RAB9A (0.76) ALDH1A1LMNAMAPTNPC1RAB9A
SCHEMBL5537277 0.79 ALDH1A1 (0.56) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL30513185 0.77 MAPT (0.52) ALDH1A1LMNAMAPTNPC1RAB9A
SCHEMBL9881353 0.77 CYP2A6 (0.54) ALDH1A1LMNANPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1072 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368259-A N- (4-methylphenyl) formamide and preparation method thereof 南京理工大学 2022-11-22 CN claimed
EP-2859069-B1 METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT FERRARA MARCELLO (IT) 2020-10-14 EP claimed
US-20190330192-A1 SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2019-10-31 US claimed
EP-3558976-A1 SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES Bayer CropScience Aktiengesellschaft (DE) 2019-10-30 EP claimed
US-9328300-B2 Method, apparatus and chemical products for treating petroleum equipment FERRARA MARCELLO (IT) 2016-05-03 US claimed
WO-2015187082-A1 NEW PLASMA LIPID LOWERING AGENTS LIPIGON PHARMACEUTICALS AB (SE) 2015-12-10 WO claimed
EP-2859069-A1 METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT Ferrara, Marcello (IT) 2015-04-15 EP claimed
CN-102557969-B Cyclic ketone derivatives and applications thereof as developers and aggregation inhibitors of amyloid protein sediments and neurofibrillary tangles USTC UNIV SCIENCE TECH CN 2015-03-18 CN claimed
WO-2013156228-A1 METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT FERRARA MARCELLO (IT) 2013-10-24 WO claimed
US-20130270157-A1 METHOD, APPARATUS AND CHEMICAL PRODUCTS FOR TREATING PETROLEUM EQUIPMENT FERRARA MARCELLO (IT) 2013-10-17 US claimed
EP-0104940-A1 3-Aryl-5,6-dihydro-1,4,2-oxathiazines and their oxides UNIROYAL, INC. (US) 1984-04-04 EP claimed
EP-0012112-B1 PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL CIBA-GEIGY AG (CH) 1983-10-05 EP claimed
EP-0012241-B1 USE OF DISAZOMETHINE COMPOUNDS FOR THE DYEING OF THERMOPLASTIC POLYESTERS IN THE MASS HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-16 EP claimed
US-4291901-A Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1981-09-29 US claimed
US-4265632-A Process for the coloration of thermoplastic polymers and polycondensates in the mass with water-insoluble disazomethine compounds HOECHST AKTIENGESELLSCHAFT (DE) 1981-05-05 US claimed
EP-0012241-A1 Use of disazomethine compounds for the dyeing of thermoplastic polyesters in the mass HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-25 EP claimed
EP-0012112-A1 Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY AG (CH) 1980-06-11 EP claimed
US-4006163-A POLYESTERS CIBA-GEIGY CORPORATION (US) 1977-02-01 US claimed
US-4002635-A FOR COLORING PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1977-01-11 US claimed
US-3954830-A Yellow methine dyes for hydrophobic textile material AMERICAN ANILINE PRODUCTS, INC. (US) 1976-05-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190330192-A1 SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES AGPS, AASDHPPT, HPD ALDH1A1 215/4885LMNA 4727/4885MAPT 4075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.