Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28078513 | 0.88 | MEN1 (0.49) | KMT2AMEN1MAPTGAAHTT | |
| SCHEMBL28031651 | 0.85 | KMT2A (0.48) | KMT2AMEN1MAPTGAAHTT | |
| SCHEMBL28032238 | 0.84 | SLC6A4 (0.47) | KMT2AMEN1MAPTGAAHTT | |
| SCHEMBL28031707 | 0.84 | ALDH1A1 (0.46) | KMT2AMEN1MAPTGAAHTT | |
| SCHEMBL28032234 | 0.81 | MEN1 (0.45) | KMT2AMEN1MAPTGAAHTT | |
| SCHEMBL28031631 | 0.80 | PTPN11 (0.47) | KMT2AMEN1MAPTPTPN11ALDH1A1 | |
| SCHEMBL28031624 | 0.80 | GAA (0.46) | KMT2AMEN1MAPTGAAHTT | |
| SCHEMBL28031775 | 0.78 | TP53 (0.45) | KMT2AMEN1MAPTGAASMN1; SMN2 | |
| SCHEMBL28031622 | 0.78 | KMT2A (0.43) | KMT2AMEN1MAPTGAAHTT | |
| SCHEMBL28032232 | 0.78 | HTT (0.42) | ARKMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017126-B | Perfluoroalkyl azole derivatives and its synthetic method | 上海麦克林生化科技有限公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-105646322-A | Perfluoroalkyl pyrrole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-105017126-A | Perfluoroalkyl pyrrole derivative and synthesis method thereof | UNIV SHANGHAI | 2015-11-04 | — | — | CN | disclosed |