SCHEMBL28032703

SCHEMBL28032703

CCC(Cc1ccccc1)(C(=O)c1ccc(Oc2ccccc2)cc1)N(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 4/20 0.49
SRD5A2 P31213 4/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44
HSP90AA1 P07900 1/20 0.44
RAB9A P51151 1/20 0.44
ACHE P22303 1/20 0.43
HPGD P15428 1/20 0.43
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
PARP10 Q53GL7 1/20 0.42
ATM Q13315 1/20 0.41
MAPK14 Q16539 2/20 0.41
PTGES O14684 1/20 0.41
ERCC5 P28715 1/20 0.40
FEN1 P39748 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14156794 0.99 NPY5R (0.47) NPY5RSRD5A2MEN1KMT2ASMN1; SMN2
SCHEMBL1554156 0.93 NPY5R (0.46) NPY5RSRD5A2MEN1KMT2ASMN1; SMN2
SCHEMBL19601362 0.92 NPY5R (0.45) NPY5RSRD5A2MEN1KMT2ANPC1
SCHEMBL4651504 0.90 ACHE (0.51) MEN1KMT2ASMN1; SMN2NPC1ALDH1A1
Benzene SCHEMBL28672020 0.87 RIPK1 (0.43) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL4650526 0.87 RIPK1 (0.43) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL19601363 0.86 MEN1 (0.41) NPY5RSRD5A2MEN1KMT2ANPC1
SCHEMBL5897070 0.85 GAA (0.50) MEN1KMT2ASMN1; SMN2NPC1ALDH1A1
SCHEMBL8899758 0.85 PPARG (0.48) MEN1KMT2ANPC1RAB9APPARG
SCHEMBL4651747 0.85 NPC1 (0.41) MEN1KMT2ASMN1; SMN2NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104974053-B Novel aminoketones photoinitiator and application in UV-LED photocuring system 天津久日新材料股份有限公司 2017-04-26 CN disclosed
CN-104974053-A Novel aminoketones photoinitiator and application in UV-LED photocuring system TIANJIN JIURI CHEMICAL CO LTD 2015-10-14 CN disclosed