SCHEMBL5897070

SCHEMBL5897070

CCC(Cc1ccccc1)(C(=O)c1ccc(OCCO)cc1)N(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.50
NR1I2 O75469 1/20 0.43
BCHE P06276 4/20 0.42
ACHE P22303 4/20 0.42
ALDH1A1 P00352 1/20 0.42
RECQL P46063 1/20 0.42
CYP19A1 P11511 1/20 0.42
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PKM P14618 1/20 0.40
EGFR P00533 2/20 0.40
MAOB P27338 1/20 0.40
PPARG P37231 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14156794 0.86 NPY5R (0.47) ACHEALDH1A1RAB9ANPC1MEN1
SCHEMBL28032703 0.85 NPY5R (0.49) ACHEALDH1A1RAB9ANPC1MEN1
SCHEMBL4651504 0.85 ACHE (0.51) ACHEALDH1A1RAB9ANPC1MAPT
SCHEMBL8899954 0.84 CHRNB2 (0.44) RAB9ANPC1MAPTSMN1; SMN2EGFR
SCHEMBL4650526 0.83 RIPK1 (0.43) RAB9ANPC1MEN1KMT2ASMN1; SMN2
Benzene SCHEMBL28672020 0.83 RIPK1 (0.43) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL8897534 0.83 HPGD (0.46) GAAALDH1A1RAB9ANPC1MAPT
SCHEMBL7929627 0.83 NR1I2 (0.47) GAANR1I2ALDH1A1MEN1KMT2A
SCHEMBL27814785 0.82 BCHE (0.43) BCHEACHEALDH1A1MAPTMEN1
SCHEMBL1630463 0.81 MAPT (0.46) GAABCHEACHEALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7040756-B2 Process for surface modifying substrates and modified substrates resulting therefrom NOVARTIS AG (CH) 2006-05-09 US disclosed
US-6852353-B2 Process for surface modifying substrates and modified substrates resulting therefrom NOVARTIS AG (CH) 2005-02-08 US disclosed
US-6835410-B2 Graft polymer overcoating NOVARTIS AG (CH) 2004-12-28 US disclosed
EP-1084428-B1 Organic articles with hydrophilic coating NOVARTIS AG (CH) 2004-11-10 EP disclosed
EP-1351780-B1 PROCESS FOR COATING A MATERIAL SURFACE NOVARTIS AG (CH) 2004-10-13 EP disclosed
EP-1299753-B1 COATED ARTICLES NOVARTIS AG (CH) 2004-05-12 EP disclosed
US-6734321-B2 Organic articles NOVARTIS AG (CH) 2004-05-11 US disclosed
EP-1395302-A1 BOTTLE-BRUSH TYPE COATINGS WITH ENTANGLED HYDROPHILIC POLYMER Novartis AG (CH) 2004-03-10 EP disclosed
US-20040018295-A1 Process for surface modifying substrates and modified substrates resulting therefrom ALCON INC. (CH) 2004-01-29 US disclosed
EP-1351780-A2 PROCESS FOR COATING A MATERIAL SURFACE Novartis Pharma GmbH (AT) 2003-10-15 EP disclosed
US-5554663-A α-aminoacetophenones as photoinitiators CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
WO-1996020796-A1 PROCESS FOR THE FUNCTIONALISATION OF SURFACES NOVARTIS AG (CH) 1996-07-11 WO disclosed
WO-1996020919-A1 FUNCTIONALISED PHOTOINITIATORS, DERIVATIVES AND MACROMERS THEREFROM AND THEIR USE NOVARTIS AG (CH) 1996-07-11 WO disclosed
WO-1996021167-A1 POLYMERS BASED ON BLOCK COPOLYMERS NOVARTIS AG (CH) 1996-07-11 WO disclosed
US-5534629-A PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed
EP-0377191-B1 Radiation-sensitive ethylenically unsaturated copolymerisable compounds, and process for their preparation BASF AG (DE) 1994-03-23 EP disclosed
EP-0284561-B1 ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS CIBA-GEIGY AG (CH) 1993-05-12 EP disclosed
US-5077402-A For photocuring pigmented systems; printing inks, lacquers CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
EP-0377191-A2 Radiation-sensitive ethylenically unsaturated copolymerisable compounds, and process for their preparation BASF Aktiengesellschaft (DE) 1990-07-11 EP disclosed
EP-0284561-A2 Alpha-aminoacetophenones as photo initiators CIBA-GEIGY AG (CH) 1988-09-28 EP disclosed