Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CPS1 | P31327 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2777908 | 0.82 | CPS1 (0.68) | SMN1; SMN2KMT2AMEN1CPS1KDM4E | |
| SCHEMBL1673485 | 0.81 | HSD11B1 (0.70) | KMT2AMEN1CPS1HSD11B1 | |
| SCHEMBL22491555 | 0.79 | MEN1 (0.59) | ALDH1A1MAPTKMT2AMEN1CPS1 | |
| SCHEMBL6210873 | 0.78 | HSD11B1 (0.68) | ALDH1A1SMN1; SMN2PKMKMT2APOLB | |
| SCHEMBL1838212 | 0.77 | MEN1 (0.61) | ALDH1A1MAPTKMT2AMEN1CPS1 | |
| SCHEMBL6209257 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1LMNACPS1 | |
| SCHEMBL6209326 | 0.76 | KMT2A (0.73) | ALDH1A1SMN1; SMN2PKMKMT2AMEN1 | |
| SCHEMBL1839628 | 0.76 | SMN1; SMN2 (0.76) | ALDH1A1SMN1; SMN2PKMKMT2ALMNA | |
| SCHEMBL18658113 | 0.75 | PTPN1 (0.82) | ALDH1A1MAPTSMN1; SMN2PKMKMT2A | |
| SCHEMBL6141006 | 0.75 | L3MBTL1 (0.61) | ALDH1A1MAPTKMT2AMEN1CPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214457-B | Azole antifungal compound and preparation method and application thereof | THE SECOND MILITARY MEDICAL UNIVERSITY (CN) | 2015-08-26 | — | — | CN | disclosed |