SCHEMBL4494873

SCHEMBL4494873

C=C(CCC(=O)OC)C(=O)OC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.62
LMNA P02545 3/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 5/20 0.44
KMT2A Q03164 2/20 0.43
HSD17B10 Q99714 2/20 0.43
HTT P42858 2/20 0.43
MAPT P10636 1/20 0.43
TET2 Q6N021 1/20 0.41
MEN1 O00255 1/20 0.41
CA12 O43570 1/20 0.40
CA14 Q9ULX7 1/20 0.40
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
RECQL P46063 1/20 0.35
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11603931 0.90 ALDH1A1 (0.52) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL28850297 0.86 TSHR (0.56) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL11699618 0.86 TSHR (0.65) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL24180351 0.85 TSHR (0.42) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL22052206 0.85 TSHR (0.42) TSHRLMNAKDM4EALDH1A1KMT2A
Dimethyl Succinate SCHEMBL11848625 0.82 TSHR (0.81) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL23161821 0.81 TSHR (0.50) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL23161369 0.81 TSHR (0.39) TSHRLMNAKDM4EALDH1A1TET2
SCHEMBL3312697 0.81 TSHR (0.62) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL7039729 0.81 ALDH1A1 (0.44) TSHRLMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117886694-A Preparation method of 2-methyl dimethyl glutarate 江苏好收成韦恩农化股份有限公司 2024-04-16 CN claimed
CN-116199579-A Preparation method of 2-methyl dimethyl glutarate 安徽华业香料股份有限公司 2023-06-02 CN claimed
EP-4695220-A1 PROCESSES FOR PRODUCING ALKYL ACRYLATE DIMERS SPECIALTY OPERATIONS FRANCE (FR) 2026-02-18 EP disclosed
EP-4695222-A1 PROCESS FOR PREPARING ESTERAMIDE COMPOUNDS SPECIALTY OPERATIONS FRANCE (FR) 2026-02-18 EP disclosed
EP-4656638-A2 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF Japan Tobacco Inc. (JP) 2025-12-03 EP disclosed
US-20250230119-A1 PROCESSES FOR PRODUCING ALKYL ACRYLATE DIMERS SPECIALTY OPERATIONS FRANCE (FR) 2025-07-17 US disclosed
US-12255351-B2 Separator for electrochemical device and method for manufacturing the same LG ENERGY SOLUTION, LTD. (KR) 2025-03-18 US disclosed
US-20240400593-A1 BIS-AMINOPHOSPHINES AS CATALYSTS FOR THE DIMERIZATION OF ALKYL ACRYLATES SPECIALTY OPERATIONS FRANCE (FR) 2024-12-05 US disclosed
WO-2024213474-A1 PROCESSES FOR PRODUCING ALKYL ACRYLATE DIMERS SPECIALTY OPERATIONS FRANCE (FR) 2024-10-17 WO disclosed
WO-2024213503-A1 PROCESS FOR PREPARING ESTERAMIDE COMPOUNDS SPECIALTY OPERATIONS FRANCE (FR) 2024-10-17 WO disclosed
EP-4419534-A1 BIS-AMINOPHOSPHINES AS CATALYSTS FOR THE DIMERIZATION OF ALKYL ACRYLATES SPECIALTY OPERATIONS FRANCE (FR) 2024-08-28 EP disclosed
JP-2000007612-A PRODUCTION OF 2-METHYLENEGLUTARIC DIESTER MITSUBISHI CHEMICALS CORP 2000-01-11 JP disclosed
EP-0762197-A1 Photographic recording material Agfa-Gevaert AG (DE) 1997-03-12 EP disclosed
EP-0666498-A2 Silver halide photographic material Agfa-Gevaert AG (DE) 1995-08-09 EP disclosed
US-5194669-A Preparation of alkyl (alkoxycarbonylcyclohexyl) cyclohexenecarboxylates and dialkyl biphenyldicarboxylates EASTMAN KODAK COMPANY (US) 1993-03-16 US disclosed
US-4927957-A TO PRODUCE ALKYL DIESTERS OF DIHYDROMUCONIC ACID RHONE-POULENC CHIMIE (FR) 1990-05-22 US disclosed
US-4889949-A CATALYST COMPOSED OF PALLADIUM SOURCE, ORGANOPHOSPHORUS COMPOUND AND HYDRACID RHONE-POULENC CHIMIE (FR) 1989-12-26 US disclosed
US-4786623-A PALLADIUM SOURCE, ORGANOPHOSPHORUS COMPOUND AND A HYDRACID RHONE-POULENC CHIMIE (FR) 1988-11-22 US disclosed
US-4621131-A TRANSESTERIFICATION WITH STERICALLY HINDERED POLYOLS; HARDENER AND BINDERS FOR HIGH SOLIDS COATINGS; PAINTS SCM CORPORATION (US) 1986-11-04 US disclosed
US-3956358-A GLUTARONITRILE, GLUTARIC ACID ESTER METAL COMPOUND CATALYST HALCON INTERNATIONAL, INC. (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400593-A1 BIS-AMINOPHOSPHINES AS CATALYSTS FOR THE DIMERIZATION OF ALKYL ACRYLATES AASDHPPT, AGPS, ACR TSHR 3889/4885LMNA 2589/4885KDM4E 3836/4885
US-20250230119-A1 PROCESSES FOR PRODUCING ALKYL ACRYLATE DIMERS HDHD5, ABHD5, HACL2 TSHR 3972/4885LMNA 3932/4885KDM4E 3857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.