Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27577875 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1CHRNB2CHRNA4L3MBTL1 | |
| SCHEMBL27415201 | 0.82 | POLB (0.34) | KDM4EALDH1A1CHRNB2CHRNA4L3MBTL1 | |
| SCHEMBL19991973 | 0.77 | CHRNB2 (0.44) | ALDH1A1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28522839 | 0.75 | SMN1; SMN2 (0.41) | KDM4EALDH1A1CHRNB2CHRNA4L3MBTL1 | |
| SCHEMBL10621262 | 0.75 | ALDH1A1 (0.50) | KDM4EALDH1A1CHRNB2CHRNA4L3MBTL1 | |
| SCHEMBL7810255 | 0.74 | NPC1 (0.38) | ALDH1A1L3MBTL1SMN1; SMN2NPC1POLB | |
| SCHEMBL28479087 | 0.73 | ALOX15 (0.52) | KDM4EALDH1A1CHRNB2CHRNA4L3MBTL1 | |
| SCHEMBL9911438 | 0.73 | CHRNB2 (0.39) | KDM4EALDH1A1CHRNB2CHRNA4L3MBTL1 | |
| SCHEMBL11410695 | 0.73 | KDM4E (0.40) | KDM4EALDH1A1CHRNB2CHRNA4L3MBTL1 | |
| SCHEMBL8786680 | 0.73 | ALDH1A1 (0.36) | KDM4EALDH1A1CHRNB2CHRNA4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061433-A | Synthetic method for 5-bromo-imidazo[1, 2-A]pyrimidine-3-carboxylate and corresponding acid thereof | HENAN VIOLET TECHNOLOGY CO LTD | 2015-11-18 | — | — | CN | disclosed |