Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033074 | 0.82 | KDM4E (0.39) | POLBPKMALDH1A1KDM4EGAA | |
| SCHEMBL12919893 | 0.77 | MAPT (0.33) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL11912103 | 0.75 | — | — | |
| SCHEMBL21561631 | 0.74 | CHRNB2 (0.35) | ALDH1A1KDM4ESMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL7810255 | 0.71 | NPC1 (0.38) | POLBALDH1A1NPC1MEN1LMNA | |
| SCHEMBL23875200 | 0.69 | — | — | |
| SCHEMBL14328602 | 0.69 | ALDH1A1 (0.39) | ALDH1A1GAANPC1MEN1LMNA | |
| SCHEMBL3391950 | 0.69 | NPC1 (0.37) | POLBALDH1A1NPC1MEN1LMNA | |
| SCHEMBL2909899 | 0.69 | PAM (0.40) | ALDH1A1NPC1MEN1LMNAMAPT | |
| SCHEMBL10308349 | 0.69 | NPC1 (0.37) | POLBALDH1A1NPC1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024116207-A1 | ADAR1 INHIBITORS AND METHODS OF USING THE SAME | AVAMMUNE THERAPEUTICS INC. (IN) | 2024-06-06 | — | — | WO | disclosed |