Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143090 | 0.83 | TDP1 (0.53) | CYP3A4CYP2C9KMT2APDE4AKDM4E | |
| SCHEMBL7001893 | 0.83 | KMT2A (0.49) | CYP1A2CYP3A4TRPA1CYP2C9CYP2C19 | |
| SCHEMBL28031195 | 0.82 | P2RY1 (0.42) | CYP1A2CYP3A4CYP2C19KMT2AMAOB | |
| SCHEMBL28822437 | 0.79 | MAPT (0.46) | TRPA1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL28035897 | 0.75 | KMT2A (0.47) | CYP1A2CYP3A4TRPA1CYP2C9CYP2C19 | |
| SCHEMBL7674701 | 0.75 | KMT2A (0.64) | CYP1A2CYP2C9CYP2C19KMT2APDE4A | |
| SCHEMBL660921 | 0.74 | LMNA (0.64) | CYP3A4KMT2ASMN1; SMN2MAOBKDM4E | |
| Ammonia Solution, Strong SCHEMBL4479019 | 0.73 | LMNA (0.61) | CYP3A4KMT2ASMN1; SMN2MAOBKDM4E | |
| Hydrochloric Acid SCHEMBL28555259 | 0.73 | LMNA (0.61) | CYP3A4KMT2ASMN1; SMN2MAOBKDM4E | |
| SCHEMBL11578278 | 0.73 | LMNA (0.61) | CYP3A4KMT2ASMN1; SMN2MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961690-A | Preparation method of 3-(4-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |
| CN-104961691-A | Preparation method of 3-(2-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |