Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 5/20 | 0.45 |
| ▸ | TDP2 | O95551 | 2/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795432 | 0.84 | GRM5 (0.50) | MAOBGRM5PARP10PARP11MAOA | |
| SCHEMBL69670 | 0.82 | MAOB (0.50) | MAOBGRM5MAOA | |
| SCHEMBL30451384 | 0.82 | MAOB (0.50) | MAOBGRM5MAOA | |
| SCHEMBL7970008 | 0.79 | GRM5 (0.52) | MAOBGRM5PGRMAOA | |
| SCHEMBL14552635 | 0.77 | MAOB (0.49) | MAOBGRM5MAOAMET | |
| SCHEMBL28140126 | 0.77 | FABP4 (0.46) | MAOBGRM5MAOAFABP4MET | |
| SCHEMBL27478944 | 0.76 | CYP11B1 (0.56) | MAOBMAOAALOX5TAAR1 | |
| SCHEMBL28246368 | 0.73 | MAOB (0.60) | MAOBGRM5MAOAFABP4 | |
| SCHEMBL1181902 | 0.73 | CTSL (0.46) | MAOBGRM5MAOA | |
| SCHEMBL4726346 | 0.73 | MAOB (0.64) | MAOBGRM5MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105213380-A | A kind of diabetes combination of oral medication | ZHU ZHONGLIANG | 2016-01-06 | — | — | CN | disclosed |
| CN-105193796-A | Diabetes mellitus resistant oral medicine composition | ZHU ZHONGLIANG | 2015-12-30 | — | — | CN | disclosed |
| CN-104994848-A | Antidiabetic bicyclic compounds | MERCK SHARP & DOHME | 2015-10-21 | — | — | CN | disclosed |