Sugi Predict

Sugi Predict / Compounds / SCHEMBL69670

SCHEMBL69670

SCHEMBL69670

O=C1CCOc2ccc(Cl)cc21

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 6/20 0.50
▸ VHL P40337 1/20 0.50
▸ ELOC Q15369 1/20 0.50
▸ ELOB Q15370 1/20 0.50
▸ MAOA P21397 1/20 0.50
▸ CTSL P07711 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ GRM5 P41594 2/20 0.47
▸ CYP19A1 P11511 1/20 0.45
▸ NOTUM Q6P988 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ PKM P14618 1/20 0.42
▸ PIK3CA P42336 1/20 0.42
▸ PIK3CB P42338 1/20 0.42
▸ PIK3CG P48736 1/20 0.42
▸ AR P10275 1/20 0.41
▸ S100A4 P26447 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30451384 1.00 MAOB (0.50) MAOBVHLELOCELOBMAOA
SCHEMBL1181902 0.89 CTSL (0.46) MAOBVHLELOCELOBMAOA
SCHEMBL4726346 0.85 MAOB (0.64) MAOBVHLELOCELOBMAOA
Hydrochloric Acid SCHEMBL27916520 0.84 MAOB (0.62) MAOBVHLELOCELOBMAOA
SCHEMBL28033205 0.82 MAOB (0.49) MAOBMAOAGRM5
SCHEMBL20554210 0.82 MAOB (0.55) MAOBMAOANPSR1GRM5MAPT
SCHEMBL69423 0.81 MAOB (0.55) MAOBVHLELOCELOBCYP19A1
SCHEMBL67612 0.78 MAOB (0.50) MAOBMAOANPSR1GRM5AR
SCHEMBL16789730 0.78 MAOB (0.50) MAOBMAOANPSR1GRM5
SCHEMBL4476431 0.78 MAOB (0.50) MAOBMAOACTSLNPSR1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10092786-B2 Fire extinguishing composition comprising aldoketones compound XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) 2018-10-09 — — US claimed
US-20160332016-A1 Fire Extinguishing Composition Comprising Aldoketones Compound NANO FIRE, LLC 2016-11-17 — — US claimed
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON INC (US) 2026-03-12 — — US disclosed
US-12509474-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2025-12-30 — — US disclosed
WO-2024140431-A1 COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF IONGEN THERAPEUTICS CO., LTD. (CN) 2024-07-04 — — WO disclosed
US-20240109920-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON, INC. 2024-04-04 — — US disclosed
US-11814404-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2023-11-14 — — US disclosed
CN-116947903-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-10-27 — — CN disclosed
CN-116496261-A 4- (1H) -imidazole derivative and medical application thereof 中国人民解放军军事科学院军事医学研究院 2023-07-28 — — CN disclosed
CN-116261564-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-06-13 — — CN disclosed
EP-4185592-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF Annexon, Inc. (US) 2023-05-31 — — EP disclosed
US-4209630-A ANTIDIABETIC AGENTS PFIZER INC. (US) 1980-06-24 — — US disclosed
EP-0011426-A1 Halogen-substituted benzopyran- and benzothiopyran-4-carboxylic acids, their preparation and pharmaceutical compositions containing the same PFIZER INC. (US) 1980-05-28 — — EP disclosed
US-4200642-A ENZYME INHIBITORS PFIZER INC. (US) 1980-04-29 — — US disclosed
US-4198426-A 2-Substituted-3-methyl-γ-pyrone tricyclic derivatives AYERST MCKENNA & HARRISON LTD. (CA) 1980-04-15 — — US disclosed
US-4189490-A 2-Substituted-3-methyl-γ-pyrone tricyclic derivatives AYERST MCKENNA & HARRISON LIMITED (CA) 1980-02-19 — — US disclosed
US-4177284-A 2-Substituted-3-methyl-γ-pyrone tricvclic derivatives and process therefor AYERST MCKENNA & HARRISON LTD. (CA) 1979-12-04 — — US disclosed
US-4169097-A GASTRIC ANTISECRETORY AGENTS MORTON-NORWICH PRODUCTS, INC. (US) 1979-09-25 — — US disclosed
US-4147795-A ENZYME INHIBITORS PFIZER INC. (US) 1979-04-03 — — US disclosed
US-4117230-A ANTIDIABETIC AGENTS PFIZER INC. (US) 1978-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109920-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFB, CFH, C9 MAOB 103/4885VHL 2295/4885ELOC 3669/4885
US-11814404-B2 Inhibitors of complement factors and uses thereof CFB, CFH, C9 MAOB 103/4885VHL 2295/4885ELOC 3669/4885
US-12509474-B2 Inhibitors of complement factors and uses thereof SSB, UACA, CFH MAOB 542/4885VHL 2453/4885ELOC 1697/4885
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFH, CFB, C5 MAOB 189/4885VHL 1773/4885ELOC 2438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.