SCHEMBL28033232

SCHEMBL28033232

CC(OCc1ccccc1)N1C=NCC1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RCE1 Q9Y256 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
DHFR P00374 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2650780 0.75 HRH3 (0.39) RCE1HRH3SLC6A2SLC6A4SLC6A3
SCHEMBL7951502 0.70 CYP2D6 (0.52) SLC6A3ALDH1A1LMNAHPGD
SCHEMBL9447134 0.70 L3MBTL1 (0.37) ALDH1A1TSHRHTT
SCHEMBL14141763 0.69 SLC6A4 (0.50) SLC6A2SLC6A4SLC6A3
SCHEMBL4970198 0.68 RCE1 (0.46) RCE1SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL5018878 0.67 RCE1 (0.49) RCE1SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL20463639 0.67 RCE1 (0.49) RCE1SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL9447192 0.67 OPRM1 (0.43) SLC6A2SLC6A4LMNATSHR
SCHEMBL1571975 0.66 TSHR (0.52) RCE1SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL15003 0.66 TSHR (0.52) RCE1SLC6A2SLC6A4SLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104961247-A Anti-scaling treatment agent for water in boiler GAO XU 2015-10-07 CN disclosed