Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | MC4R | P32245 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447077 | 0.87 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1MC4R | |
| SCHEMBL28047160 | 0.82 | OPRM1 (0.53) | OPRM1OPRD1OPRK1OPRL1CYP17A1 | |
| Hydrochloric Acid SCHEMBL9280960 | 0.81 | CYP2C19 (0.37) | OPRM1OPRD1OPRK1OPRL1SLC6A4 | |
| Hydrochloric Acid SCHEMBL28274952 | 0.81 | OPRM1 (0.52) | OPRM1OPRD1OPRK1OPRL1CYP17A1 | |
| Hydrochloric Acid SCHEMBL9850163 | 0.80 | OPRL1 (0.38) | OPRM1OPRD1OPRK1OPRL1SLC6A4 | |
| SCHEMBL27972359 | 0.77 | CYP2D6 (0.52) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL7951502 | 0.77 | CYP2D6 (0.52) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL9447134 | 0.76 | L3MBTL1 (0.37) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL11830842 | 0.74 | LMNA (0.36) | OPRM1OPRD1LMNACYP1A2CYP3A4 | |
| SCHEMBL4800291 | 0.72 | OPRM1 (0.56) | OPRM1OPRD1OPRK1OPRL1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107385449-A | A kind of corrosion inhibiter preparation method and application for suppressing carbon steel sour corrosion | 中国石油大学(华东) | 2017-11-24 | — | — | CN | disclosed |
| US-5250286-A | Treatment of chronic obstructive pulmonary disease (COPD) by inhalation of an imidazoline | AEGIS TECHNOLOGY, INC. (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0527925-A4 | TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) BY INHALATION OF AN IMIDAZOLINE | — | 1993-09-15 | — | — | EP | disclosed |
| EP-0527925-A1 | TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) BY INHALATION OF AN IMIDAZOLINE | AEGIS TECHNOLOGIE, INC. (US) | 1993-02-24 | — | — | EP | disclosed |
| US-5096916-A | Administering tolazoline | AEGIS TECHNOLOGY, INC. (US) | 1992-03-17 | — | — | US | disclosed |
| WO-1991016891-A1 | TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) BY INHALATION OF AN IMIDAZOLINE | AEGIS TECHNOLOGY, INC. (US) | 1991-11-14 | — | — | WO | disclosed |