Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033825 | 0.80 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2PRNPMAPK14 | |
| SCHEMBL28033278 | 0.80 | ALDH1A1 (0.48) | NPC1RAB9ASMN1; SMN2PRNPMAPK14 | |
| SCHEMBL6319469 | 0.79 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2MAPK14MAPT | |
| SCHEMBL10768583 | 0.76 | HPGD (0.57) | NPC1RAB9ASMN1; SMN2MAPTCA1 | |
| SCHEMBL28033321 | 0.75 | GAA (0.51) | RAB9AMAPTCA1CA2ALDH1A1 | |
| SCHEMBL20142071 | 0.73 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2PRNPGSK3A | |
| SCHEMBL8746213 | 0.72 | MYC (0.47) | NPC1RAB9AGSK3BMAPK14MAPT | |
| SCHEMBL28033271 | 0.72 | CES2 (0.44) | NPC1RAB9ASMN1; SMN2PRNPMAPK14 | |
| SCHEMBL3433075 | 0.72 | CA2 (0.67) | NPC1RAB9AGSK3BMAPTCA1 | |
| SCHEMBL28033274 | 0.72 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2MAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870464-A | polymannosides, method for the production thereof and their use as medicaments | CENTRE NAT RECH SCIENT | 2015-08-26 | — | — | CN | disclosed |