Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006799 | 0.79 | CES2 (0.64) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL4703400 | 0.78 | CES2 (0.61) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL30976528 | 0.78 | CES2 (0.61) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL3237973 | 0.78 | CES2 (0.61) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL2441765 | 0.76 | CES2 (0.59) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL1279794 | 0.76 | ALDH1A1 (0.61) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL10349262 | 0.76 | CES2 (0.59) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL3777401 | 0.74 | LMNA (0.61) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL13127271 | 0.73 | CES2 (0.55) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL27430241 | 0.73 | CES2 (0.55) | CES2CES1L3MBTL1LMNANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926720-B | A kind of chiral nitrogen sulphur bidentate ligand and its synthetic method and application | 同济大学 | 2018-02-09 | — | — | CN | claimed |
| CN-104926720-A | Chiral nitrogen-sulfur bidentate ligand and synthesis method and application thereof | UNIV TONGJI | 2015-09-23 | — | — | CN | claimed |
| CN-104926720-B | A kind of chiral nitrogen sulphur bidentate ligand and its synthetic method and application | 同济大学 | 2018-02-09 | — | — | CN | disclosed |
| CN-104926720-A | Chiral nitrogen-sulfur bidentate ligand and synthesis method and application thereof | UNIV TONGJI | 2015-09-23 | — | — | CN | disclosed |
| CN-104926720-A | Chiral nitrogen-sulfur bidentate ligand and synthesis method and application thereof | UNIV TONGJI | 2015-09-23 | — | — | CN | disclosed |