Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976528 | 1.00 | CES2 (0.61) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL2006799 | 0.84 | CES2 (0.64) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL3237973 | 0.83 | CES2 (0.61) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL10349262 | 0.81 | CES2 (0.59) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL2441765 | 0.81 | CES2 (0.59) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL1279794 | 0.81 | ALDH1A1 (0.61) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL3777401 | 0.79 | LMNA (0.61) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL13127271 | 0.78 | CES2 (0.55) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL27430241 | 0.78 | CES2 (0.55) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL28033327 | 0.78 | CES2 (0.55) | CES2CES1L3MBTL1LMNANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233756-A | Pharmaceutically acceptable salt of oxopyridine amide derivative and preparation method thereof | 李伟 | 2020-06-05 | — | — | CN | claimed |
| CN-117736140-A | Pyridine alkaloid compound in purslane, and extraction and separation method and application thereof | 辽宁中医药大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-116601150-A | Fused bicyclic RAF inhibitors and methods of use thereof | 爵士制药爱尔兰有限公司 | 2023-08-15 | — | — | CN | disclosed |
| EP-3506754-B1 | PICOLINAMIDE N-OXIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3506754-B1 | PICOLINAMIDE N-OXIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2023-08-09 | — | — | EP | disclosed |
| US-11639334-B2 | Methods for synthesis of oxypicolinamides | CORTEVA AGRISCIENCE LLC (US) | 2023-05-02 | — | — | US | disclosed |
| US-11639334-B2 | Methods for synthesis of oxypicolinamides | CORTEVA AGRISCIENCE LLC (US) | 2023-05-02 | — | — | US | disclosed |
| CN-111233756-A | Pharmaceutically acceptable salt of oxopyridine amide derivative and preparation method thereof | 李伟 | 2020-06-05 | — | — | CN | disclosed |
| WO-2020081382-A1 | METHODS FOR SYTHESIS OF OXYPICOLINAMIDES | DOW AGROSCIENCES LLC (US) | 2020-04-23 | — | — | WO | disclosed |
| EP-3506755-A4 | PICOLINAMIDE N-OXIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow AgroSciences LLC (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-1234826-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234824-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234823-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234825-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2002050091-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |
| EP-1204643-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | Dow AgroSciences LLC (US) | 2002-05-15 | — | — | EP | disclosed |
| EP-1196388-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | Dow AgroSciences LLC (US) | 2002-04-17 | — | — | EP | disclosed |
| US-6355660-B1 | HETEROCYCLIC FUNGICIDES SUBSTITUTED WITH AMIDE GROUPS | DOW AGROSCIENCES LLC | 2002-03-12 | — | — | US | disclosed |
| WO-2001014339-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2001-03-01 | — | — | WO | disclosed |
| WO-2001005769-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639334-B2 | Methods for synthesis of oxypicolinamides | CYP51A1, CYP4X1, CYP4F3 | CES2 43/4885CES1 351/4885L3MBTL1 3794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.