Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 3/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.31 |
| ▸ | PTPRB | P23467 | 3/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28034000 | 0.93 | PNMT (0.35) | NPC1RAB9AGSTA1GSTP1 | |
| SCHEMBL28293410 | 0.93 | NPC1 (0.30) | NPC1RAB9A | |
| SCHEMBL28033425 | 0.92 | NPC1 (0.34) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL28033426 | 0.86 | GSTA1 (0.34) | NPC1RAB9AGSTA1GSTP1PTPRC | |
| SCHEMBL28293411 | 0.85 | PNMT (0.32) | — | |
| SCHEMBL28033483 | 0.85 | RAB9A (0.35) | NPC1RAB9A | |
| SCHEMBL28293481 | 0.85 | GABRP (0.32) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL28033430 | 0.85 | PNMT (0.36) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL28293409 | 0.81 | NPC1 (0.31) | NPC1RAB9AGSTA1GSTP1 | |
| SCHEMBL28033429 | 0.78 | GABRP (0.34) | NPC1RAB9AGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073807-A | Curable resin composition, cured product, and optical article | NIPPON STEEL & SUMIKIN CHEM CO | 2015-11-18 | — | — | CN | disclosed |