Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033014 | 0.79 | TUBB4A (0.50) | ALOX5ALDH1A1KMT2ALMNARAB9A | |
| SCHEMBL15572668 | 0.70 | ALDH1A1 (0.73) | ALDH1A1KMT2ALMNARAB9AMITF | |
| SCHEMBL27983671 | 0.65 | TUBB4A (0.55) | ALDH1A1KMT2ALMNANPSR1MAPT | |
| SCHEMBL27611388 | 0.65 | AHR (0.36) | ALOX5ALDH1A1KMT2ALMNARAB9A | |
| Carbazole SCHEMBL3924065 | 0.65 | ALDH1A1 (0.58) | ALDH1A1KMT2ALMNARAB9AMAPT | |
| SCHEMBL3426478 | 0.64 | KDM4E (0.66) | ALDH1A1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL27948877 | 0.64 | KDM4E (0.68) | ALDH1A1KMT2ALMNARAB9ANPSR1 | |
| SCHEMBL10478444 | 0.64 | KDM4E (0.53) | ALOX5ALDH1A1KMT2ALMNARAB9A | |
| SCHEMBL9442793 | 0.64 | KDM4E (0.56) | ALDH1A1KMT2ARAB9AMAPTKDM4E | |
| SCHEMBL28165688 | 0.63 | KDM4E (0.54) | ALDH1A1KMT2ALMNARAB9AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061287-A | N-substituted benzenesulfonyl-3-propionyl indole derivative, preparation method and application | UNIV HENAN SCIENCE & TECH | 2015-11-18 | — | — | CN | claimed |
| CN-105061287-A | N-substituted benzenesulfonyl-3-propionyl indole derivative, preparation method and application | UNIV HENAN SCIENCE & TECH | 2015-11-18 | — | — | CN | disclosed |