Carbazole

Carbazole

SCHEMBL3924065

CCC(=O)O.c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.58
GPR3 P46089 1/20 0.58
HSD17B10 Q99714 1/20 0.58
KDM4E B2RXH2 5/20 0.56
MAPT P10636 3/20 0.56
GAA P10253 2/20 0.56
CASP1 P29466 1/20 0.56
CASP7 P55210 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.53
MEN1 O00255 1/20 0.53
HCRTR1 O43613 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
KIF11 P52732 2/20 0.52
EGFR P00533 1/20 0.50
AHR P35869 1/20 0.50
LMNA P02545 1/20 0.50
GLA P06280 1/20 0.50
HPGD P15428 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridone SCHEMBL28843913 0.90 GAA (0.67) ALDH1A1KDM4EMAPTGAACASP1
Carbazole SCHEMBL4314436 0.88 GABRP (0.55) ALDH1A1GPR3HSD17B10KDM4EMAPT
Carbazole SCHEMBL30528395 0.85 ALDH1A1 (0.67) ALDH1A1GPR3HSD17B10KDM4EMAPT
Carbazole SCHEMBL4786151 0.85 ALDH1A1 (0.67) ALDH1A1GPR3HSD17B10KDM4EMAPT
Carbazole SCHEMBL8411559 0.84 ALDH1A1 (0.74) ALDH1A1GPR3HSD17B10KDM4EMAPT
Carbazole SCHEMBL573588 0.82 ALDH1A1 (0.70) ALDH1A1GPR3HSD17B10KDM4EMAPT
Carbazole SCHEMBL28171971 0.82 ALDH1A1 (0.70) ALDH1A1GPR3HSD17B10KDM4EMAPT
Carbazole SCHEMBL28847016 0.82 OXER1 (0.61) ALDH1A1HSD17B10KDM4EGAAMEN1
Carbazole SCHEMBL28852407 0.82 ALDH1A1 (0.78) ALDH1A1GPR3HSD17B10KDM4EMAPT
Carbazole SCHEMBL9398513 0.81 OXER1 (0.64) ALDH1A1HSD17B10KDM4EGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115931807-A Method for detecting polymer chain conformation grafted on surface in flow field in real time by adopting non-radiative energy transfer technology 南京大学 2023-04-07 CN disclosed
CN-104977644-B Polarization plates and liquid crystal display panel 东友精细化工有限公司 2019-06-07 CN disclosed
CN-101432388-B Amorphous polymers with chromophoric side groups DU PONT 2013-07-24 CN disclosed
CN-103124924-A Photorefractive composition responsive to multiple laser wavelengths across the visible light spectrum NITTO DENKO CORP 2013-05-29 CN disclosed
US-8287767-B2 Amorphous polymers with pendant chromogenic groups E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-10-16 US disclosed
US-20090279160-A1 AMORPHOUS POLYMERS WITH PENDANT CHROMOGENIC GROUPS E. I. DUPONT DE NEMOURS AND COMPANY (US) 2009-11-12 US disclosed
CN-101432388-A Amorphous polymers with chromophoric side groups DU PONT (US) 2009-05-13 CN disclosed
EP-2032670-A1 AMORPHOUS POLYMERS WITH PENDANT CHROMOGENIC GROUPS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-03-11 EP disclosed
WO-2007149090-A1 AMORPHOUS POLYMERS WITH PENDANT CHROMOGENIC GROUPS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-27 WO disclosed
US-5420289-A ANTIINFLAMMATORY AGENTS, ANTIALLERGENS AND CYTOPROTECTIVE AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1995-05-30 US disclosed
US-5229516-A Antiinflammatory agents, antiallergens and cytoprotective agents AMERICAN HOME PRODUCTS CORPORATION (US) 1993-07-20 US disclosed
EP-0502106-A1 SUBSTITUTED INDOLE-, INDENE-, PYRANOINDOLE- AND TETRAHYDROCARBAZOLE- ALKANOIC ACID DERIVATIVES AS INHIBITORS OF PLA2 AND LIPOXYGENASE AMERICAN HOME PRODUCTS CORPORATION (US) 1992-09-09 EP disclosed
WO-1991006537-A2 SUBSTITUTED INDOLE-, INDENE-, PYRANOINDOLE- AND TETRAHYDROCARBAZOLE- ALKANOIC ACID DERIVATIVES AS INHIBITORS OF PLA2 AND LIPOXYGENASE AMERICAN HOME PRODUCTS CORPORATION (US) 1991-05-16 WO disclosed