Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.61 |
| ▸ | CDK8 | P49336 | 2/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27856065 | 0.83 | CYP11B1 (0.61) | CYP11B1CYP11B2CDK8PHGDH | |
| SCHEMBL31342013 | 0.83 | CYP11B1 (0.72) | CYP11B1CYP11B2CDK8PHGDHNCF1 | |
| SCHEMBL14861127 | 0.81 | LATS1 (0.52) | HRH4PHGDH | |
| SCHEMBL6263602 | 0.80 | CYP11B1 (0.66) | CYP11B1CYP11B2CDK8NCF1HTR3A | |
| SCHEMBL5820339 | 0.80 | CYP11B1 (0.67) | CYP11B1CYP11B2CDK8NCF1 | |
| SCHEMBL6002177 | 0.79 | HTR1A (0.62) | HRH4NCF1HTR3AHTR3EHTR3B | |
| SCHEMBL27359418 | 0.77 | HTR1A (0.61) | HRH4NCF1HTR3AHTR3EHTR3B | |
| SCHEMBL6359045 | 0.75 | CYP11B1 (0.60) | CYP11B1CYP11B2CDK8NCF1HTR3A | |
| SCHEMBL30572642 | 0.74 | CYP11B2 (0.57) | CYP11B1CYP11B2CDK8PHGDHNCF1 | |
| SCHEMBL17144774 | 0.73 | NCF1 (0.56) | HRH4NCF1HTR3AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104918941-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2015-09-16 | — | — | CN | disclosed |