Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3464239 | 0.83 | HPGD (0.39) | TSHRHPGDHSD17B10MAPK1CYP3A4 | |
| SCHEMBL6601793 | 0.80 | ALDH1A1 (0.41) | TSHRHPGDHSD17B10MAPK1CYP3A4 | |
| SCHEMBL27982832 | 0.79 | HPGD (0.34) | TSHRHPGDHSD17B10MAPK1CA12 | |
| SCHEMBL16395176 | 0.79 | HTR2C (0.38) | TSHRHPGDHSD17B10MAPK1CYP3A4 | |
| SCHEMBL4884473 | 0.79 | ADRA2A (0.40) | TSHRHPGDHSD17B10MAPK1CYP3A4 | |
| SCHEMBL3971417 | 0.77 | KDM4E (0.46) | HPGDHSD17B10CYP3A4GAAHTR2A | |
| SCHEMBL7688247 | 0.77 | KDM4E (0.42) | HPGDHSD17B10CYP3A4GAAALDH1A1 | |
| SCHEMBL6197092 | 0.76 | ALDH1A1 (0.41) | TSHRHPGDHSD17B10MAPK1CYP3A4 | |
| SCHEMBL27982834 | 0.76 | ALDH1A1 (0.35) | TSHRHPGDHSD17B10MAPK1LIG1 | |
| SCHEMBL15665568 | 0.76 | RAB9A (0.39) | TSHRHPGDCYP3A4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103228643-B | As the benzoxazole derivative of histamine h 4 receptor part | BIOPROJET (FR) | 2015-11-25 | — | — | CN | claimed |
| CN-103228643-B | As the benzoxazole derivative of histamine h 4 receptor part | BIOPROJET (FR) | 2015-11-25 | — | — | CN | disclosed |