Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 10/20 | 0.38 |
| ▸ | HTR2A | P28223 | 6/20 | 0.38 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928071 | 0.86 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CTSHRGAA | |
| SCHEMBL3464239 | 0.83 | HPGD (0.39) | ADRA2AADRA2BADRA2CTSHRGAA | |
| SCHEMBL16395176 | 0.82 | HTR2C (0.38) | ADRA2AADRA2BADRA2CTSHRGAA | |
| SCHEMBL6601793 | 0.80 | ALDH1A1 (0.41) | ADRA2AADRA2BADRA2CTSHRGAA | |
| SCHEMBL28033646 | 0.79 | TSHR (0.36) | ADRA2AADRA2BADRA2CTSHRGAA | |
| SCHEMBL7688247 | 0.77 | KDM4E (0.42) | GAAHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL3971417 | 0.77 | KDM4E (0.46) | GAAHTR2AHSD17B10HPGDALDH1A1 | |
| SCHEMBL6197092 | 0.76 | ALDH1A1 (0.41) | ADRA2AADRA2BADRA2CTSHRGAA | |
| SCHEMBL16394920 | 0.76 | HTR2C (0.39) | ADRA2AADRA2BADRA2CTSHRGAA | |
| SCHEMBL27982832 | 0.76 | HPGD (0.34) | ADRA2AADRA2BADRA2CTSHRHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078099-B1 | SUBSTITUTED PHENYL (THIONO)CARBAMATES, HERBICIDAL COMPOSITIONS CONTAINING THE SAME AS ACIVE INGREDIENT AND METHOD OF CONTROLLING WEEDS | KURARAY CO., LTD. (JP) | 1985-11-27 | — | — | EP | claimed |
| CN-107266382-B | Heteroarylpiperidine and piperazine derivatives as fungicides | 拜耳知识产权有限责任公司 | 2020-10-27 | — | — | CN | disclosed |
| US-10426169-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-10-01 | — | — | US | disclosed |
| EP-2921484-B1 | OXAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2921485-B1 | ISOXAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | disclosed |
| US-20180103641-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-19 | — | — | US | disclosed |
| EP-2921495-B1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| CN-107266383-A | It is used as the heteroaryl piperidine and heteroaryl based piperazine derivative of bactericide | 拜耳知识产权有限责任公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-107266382-A | It is used as the heteroaryl piperidine and heteroaryl based piperazine derivative of bactericide | 拜耳知识产权有限责任公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-107253947-A | It is used as the heteroaryl piperidine and heteroaryl based piperazine derivative of bactericide | 拜耳知识产权有限责任公司 | 2017-10-17 | — | — | CN | disclosed |
| EP-2921485-A1 | ISOXAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921484-A1 | OXAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921481-A1 | 4-PIPERIDINE CARBOXYLIC ACID DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921491-A1 | INTERMEDIATES FOR THE PRODUCTION OF HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2921494-A1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| US-20150024935-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-22 | — | — | US | disclosed |
| US-20080293939-A1 | QUINAZOLINONE DERIVATIVES USEFUL AS ANTI-HYPERALGESIC AGENTS | CULSHAW ANDREW JAMES | 2008-11-27 | — | — | US | disclosed |
| CN-100432059-C | Quinazolinone derivatives useful as anti-hyperalgesic agents | NOVARTIS AG (CH) | 2008-11-12 | — | — | CN | disclosed |
| US-20060154942-A1 | Quinazolinone derivatives useful as anti-hyperalgesic agents | CULSHAW ANDREW J | 2006-07-13 | — | — | US | disclosed |
| CN-1711249-A | Quinazolinone derivatives useful as anti-hyperalgesic agents | NOVARTIS AG (CH) | 2005-12-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293939-A1 | QUINAZOLINONE DERIVATIVES USEFUL AS ANTI-HYPERALGESIC AGENTS | OPRK1, OPRL1, TRPV1 | ADRA2A 104/4885ADRA2B 218/4885ADRA2C 82/4885 |
| US-10426169-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | RB1, RBX1, RRP12 | ADRA2A 1209/4885ADRA2B 1883/4885ADRA2C 1245/4885 |
| US-20180103641-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | RB1, RBX1, RRP12 | ADRA2A 1209/4885ADRA2B 1883/4885ADRA2C 1245/4885 |
| US-20150024935-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | RB1, RBX1, RRP12 | ADRA2A 1371/4885ADRA2B 1938/4885ADRA2C 1457/4885 |
| US-20060154942-A1 | Quinazolinone derivatives useful as anti-hyperalgesic agents | OPRK1, OPRL1, TRPV1 | ADRA2A 104/4885ADRA2B 218/4885ADRA2C 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.