Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182010 | 0.78 | CES2 (0.71) | HPGDHTTALDH1A1NPC1HSD17B10 | |
| SCHEMBL6319469 | 0.76 | NPC1 (0.63) | HPGDHTTALDH1A1NPC1HSD17B10 | |
| SCHEMBL6494787 | 0.74 | HPGD (0.72) | HPGDHTTALDH1A1NPC1HSD17B10 | |
| SCHEMBL28033271 | 0.72 | CES2 (0.44) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5217935 | 0.72 | MAPT (0.55) | HPGDHTTALDH1A1NPC1HSD17B10 | |
| Cyclopentane SCHEMBL8081415 | 0.72 | HPGDS (0.63) | HPGDHTTALDH1A1NPC1HSD17B10 | |
| SCHEMBL231104 | 0.71 | MAPK13 (0.60) | ALDH1A1LMNAGAA | |
| SCHEMBL15672439 | 0.71 | MAPK13 (0.41) | ALDH1A1NPC1HSD17B10KMT2ARAB9A | |
| SCHEMBL1631557 | 0.70 | — | — | |
| SCHEMBL1636287 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870464-A | polymannosides, method for the production thereof and their use as medicaments | CENTRE NAT RECH SCIENT | 2015-08-26 | — | — | CN | disclosed |