Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | CASP1 | P29466 | 1/20 | 0.72 |
| ▸ | CASP7 | P55210 | 1/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.72 |
| ▸ | RELA | Q04206 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182010 | 0.91 | CES2 (0.71) | HPGDALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7862027 | 0.85 | ALDH1A1 (1.00) | HPGDALDH1A1LMNAMEN1KMT2A | |
| Cyclopentane SCHEMBL8081415 | 0.84 | HPGDS (0.63) | HPGDALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6793430 | 0.79 | HPGDS (0.83) | HPGDALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11532822 | 0.78 | HPGD (0.73) | HPGDALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9148337 | 0.77 | LMNA (0.85) | HPGDALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7870469 | 0.77 | ALDH1A1 (0.89) | HPGDALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL826317 | 0.76 | — | — | |
| SCHEMBL158020 | 0.76 | HPGDS (1.00) | HPGDALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1066873 | 0.75 | CES2 (1.00) | HPGDALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852458-B2 | Electrophotographic photoreceptor, and electrophotographic apparatus using the same | FUJI ELECTRIC IMAGING DEVICE CO., LTD. (JP) | 2005-02-08 | — | — | US | disclosed |
| US-6825359-B2 | USEFUL AS AN ELECTRON TRANSPORT SUBSTANCE IN AN ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ORGANIC ELECTROLUMINESENCE (EL) DEVICE | FUJI ELECTRIC IMAGING DEVICE CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030219664-A1 | Electrophotographic photoreceptor, and electrophotographic apparatus using the same | FUJI ELECTRIC IMAGING DEVICE CO., LTD. (JP) | 2003-11-27 | — | — | US | disclosed |
| US-20030195359-A1 | Quinomethane compounds | FUJI ELECTRIC IMAGING DEVICE CO., LTD. (JP) | 2003-10-16 | — | — | US | disclosed |
| US-5420224-A | Films and fibers with benzoxazole groups | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1995-05-30 | — | — | US | disclosed |
| US-5354836-A | Polyarylene ether ketone, where at least one ring of the aromatic ketone unit is a thiophene ring | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1994-10-11 | — | — | US | disclosed |
| US-5266677-A | Aromatic polyamides | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1993-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195359-A1 | Quinomethane compounds | ALDH1A2, NR2E3, CRY1 | HPGD 2144/4885ALDH1A1 36/4885LMNA 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.