Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.76 |
| ▸ | MITF | O75030 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | SNCA | P37840 | 2/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.64 |
| ▸ | NQO2 | P16083 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491689 | 1.00 | PTPN1 (0.76) | PTPN1MITFMEN1KMT2APOLB | |
| SCHEMBL20284430 | 0.95 | PTPN1 (0.86) | PTPN1MITFMEN1KMT2APOLB | |
| SCHEMBL10684470 | 0.92 | PTPN1 (0.88) | PTPN1MITFMEN1KMT2APOLB | |
| SCHEMBL8420639 | 0.90 | DEGS1 (0.75) | PTPN1MEN1KMT2APOLBTDP1 | |
| SCHEMBL900928 | 0.90 | DEGS1 (0.75) | PTPN1MEN1KMT2APOLBTDP1 | |
| SCHEMBL899585 | 0.90 | DEGS1 (0.75) | PTPN1MEN1KMT2APOLBTDP1 | |
| SCHEMBL8768807 | 0.86 | MEN1 (0.86) | PTPN1MITFMEN1KMT2APOLB | |
| SCHEMBL8770854 | 0.86 | PTPN1 (0.79) | PTPN1MITFMEN1KMT2APOLB | |
| SCHEMBL18938397 | 0.86 | NPC1 (0.77) | PTPN1MITFMEN1KMT2APOLB | |
| SCHEMBL3639776 | 0.85 | MITF (1.00) | PTPN1MITFMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055007-A1 | PROSTAGLANDIN ANALOGS AND USES THEREOF | Lifex Biolabs, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| US-20210139435-A1 | PROSTAGLANDIN ANALOGS AND USES THEREOF | Lifex Biolabs, Inc. | 2021-05-13 | — | — | US | disclosed |
| US-8026370-B2 | Peroxisome proliferator antagonist; hyperlipemia agents; arteriosclerosis; antiischemic agents | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-27 | — | — | US | disclosed |
| US-20080167307-A1 | Carboxylic Acid Derivative Containing Thiazole Ring and Pharmaceutical Use Thereof | MITSUBISHI PHAMA CORPORATION (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| CN-101068797-A | Carboxylic acid derivative containing thiazole ring and pharmaceutical use thereof | MITSUBISHI PHARMA CORP (JP) | 2007-11-07 | — | — | CN | disclosed |
| EP-1816128-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
| CN-1543451-A | Receptor modulators activated by peroxizonal proliferators (ppar) | — | 2004-11-03 | — | — | CN | disclosed |
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167307-A1 | Carboxylic Acid Derivative Containing Thiazole Ring and Pharmaceutical Use Thereof | PPARA, PPARD, PPARG | PTPN1 1803/4885MITF 1454/4885MEN1 4667/4885 |
| US-20210139435-A1 | PROSTAGLANDIN ANALOGS AND USES THEREOF | PTGDR, NR3C1, PTGIR | PTPN1 1903/4885MITF 463/4885MEN1 3410/4885 |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | PTPN1 1824/4885MITF 3436/4885MEN1 4860/4885 |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | PTPN1 1691/4885MITF 3231/4885MEN1 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.