SCHEMBL28034550

SCHEMBL28034550

OC[C@@H](F)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 5/20 0.45
LMNA P02545 1/20 0.41
HTR2A P28223 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
GSR P00390 1/20 0.39
KDM4E B2RXH2 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP2D6 P10635 1/20 0.39
SRC P12931 1/20 0.39
TSHR P16473 2/20 0.38
DPP4 P27487 2/20 0.38
F2 P00734 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2078925 1.00 TRPA1 (0.45) TRPA1LMNAHTR2ATAAR1GSR
SCHEMBL5597894 1.00 TRPA1 (0.45) TRPA1LMNAHTR2ATAAR1GSR
SCHEMBL17151064 0.86 CHRNB2 (0.47) LMNATAAR1CYP2D6TSHR
SCHEMBL11044379 0.85 ALDH1A1 (0.43) TRPA1LMNAKDM4ECYP2D6SRC
SCHEMBL27881387 0.80 TRPA1 (0.48) TRPA1LMNAHTR2ATAAR1KDM4E
SCHEMBL28146626 0.77 TRPA1 (0.42) TRPA1LMNAKDM4E
SCHEMBL10846548 0.77 TRPA1 (0.41) TRPA1LMNAHTR2ATAAR1GSR
SCHEMBL1538461 0.76 TAAR1 (0.42) LMNAHTR2ATAAR1TSHRDPP4
SCHEMBL3973130 0.76 TAAR1 (0.42) LMNAHTR2ATAAR1TSHRDPP4
SCHEMBL746303 0.75 CA1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105087671-A Method for preparing (S)-fluoro-phenyl ethanol with penicillium UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-11-25 CN disclosed
CN-105087671-A Method for preparing (S)-fluoro-phenyl ethanol with penicillium UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-11-25 CN disclosed
CN-105087668-A Method for preparing (S)-fluoro-phenyl ethanol with penicillium UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-11-25 CN disclosed