SCHEMBL3973130

SCHEMBL3973130

[CH2]CC(F)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.42
HTR2A P28223 2/20 0.42
DPP4 P27487 2/20 0.39
TSHR P16473 2/20 0.39
F2 P00734 1/20 0.39
HRH1 P35367 2/20 0.39
MTOR P42345 1/20 0.39
RAB9A P51151 1/20 0.39
GRM7 Q14831 1/20 0.39
LMNA P02545 1/20 0.37
CYP3A4 P08684 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4890479 0.82 HRH1 (0.39) TAAR1HTR2ADPP4TSHRF2
SCHEMBL4126387 0.79 TAAR1 (0.44) TAAR1HTR2ADPP4TSHRF2
SCHEMBL4890470 0.79 HRH1 (0.39) TAAR1HTR2ADPP4TSHRF2
SCHEMBL1538461 0.78 TAAR1 (0.42) TAAR1HTR2ADPP4TSHRF2
SCHEMBL94275 0.77 HTR2A (0.52) TAAR1HTR2ADPP4TSHRF2
SCHEMBL9350831 0.76 HTR2A (0.40) TAAR1HTR2ADPP4TSHRF2
SCHEMBL15560207 0.76 TSHR (0.43) TAAR1HTR2ADPP4TSHRF2
SCHEMBL3898638 0.76 LMNA (0.52) TAAR1HTR2AHRH1LMNA
SCHEMBL17816146 0.76 LMNA (0.52) TAAR1HTR2AHRH1LMNA
SCHEMBL5597894 0.76 TRPA1 (0.45) TAAR1HTR2ADPP4TSHRF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115380211-A Refining process and refined product 日本水产株式会社 2022-11-22 CN claimed
CN-105102456-B Azaquinazoline inhibitors of atypical protein kinase C 癌症研究技术有限公司 2017-11-14 CN claimed
CN-101180266-A Alpha ketoamide compounds as cysteine protease inhibitors APPLERA CORP (US) 2008-05-14 CN claimed
CN-1512983-A Compounds and compositions as cathepsins inhibitors AXYSҩ�﹫˾ 2004-07-14 CN claimed
US-5461074-A Dipropargyl containing aryl/alkyl sulfur/or sulfonyl/or sulfoxide terminated aminodiol compounds are used as renin inhibitor; therpeutical G.D. SEARLE & CO. (US) 1995-10-24 US claimed
US-5317039-A Renin inhibitors with peptides G. D. SEARLE & CO. (US) 1994-05-31 US claimed
US-5314920-A Renin inhibitors G. D. SEARLE & CO. (US) 1994-05-24 US claimed
US-5312838-A β-alanineamide aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension G. D. SEARLE & CO. (US) 1994-05-17 US claimed
US-5268391-A Cardiovascular disorders C. D. SEARLE & CO. (US) 1993-12-07 US claimed
US-5246969-A Oligopeptides as renin inhibitors G. D. SEARLE & CO. (US) 1993-09-21 US claimed
WO-2024101336-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND 国立大学法人京都大学 2024-05-16 WO disclosed
US-20240075407-A1 METHOD OF PURIFICATION AND PURIFIED PRODUCTS NISSUI CORPORATION (JP) 2024-03-07 US disclosed
CN-116830317-A Positive electrode slurry and secondary battery prepared from same 宁德时代新能源科技股份有限公司 2023-09-29 CN disclosed
CN-116589494-A Magnesium/calcium borate, and preparation method and application thereof 浙江大学杭州国际科创中心 2023-08-15 CN disclosed
WO-2023097432-A1 POSITIVE ELECTRODE SLURRY, AND SECONDARY BATTERY PREPARED THEREFROM 宁德时代新能源科技股份有限公司 2023-06-08 WO disclosed
US-4420477-A ANTIBIOTICS, BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-12-13 US disclosed
EP-0095029-A1 5-Thio-tetrazol compounds and their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-11-30 EP disclosed
US-4405617-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-09-20 US disclosed
EP-0033965-A2 New cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-08-19 EP disclosed
EP-0029998-A2 Cephem compounds, processes for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-06-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240075407-A1 METHOD OF PURIFICATION AND PURIFIED PRODUCTS SPOP, SSRP1, SPIN4 TAAR1 4602/4885HTR2A 2537/4885DPP4 2925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.