1-Naphthol

1-Naphthol

SCHEMBL28034918

Nc1ccc(F)cc1.Oc1cccc2ccccc12

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.63
PLAU P00749 1/20 0.56
CTDSP1 Q9GZU7 1/20 0.56
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
KEAP1 Q14145 1/20 0.47
HSD17B10 Q99714 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HDAC3 O15379 1/20 0.44
IDO1 P14902 1/20 0.44
EP300 Q09472 1/20 0.44
KAT2B Q92831 1/20 0.44
KAT8 Q9H7Z6 1/20 0.44
NCOR2 Q9Y618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL8410220 0.90 CYP1A2 (0.77) CYP1A2PLAUCTDSP1ALDH1A1CYP3A4
1-Naphthol SCHEMBL9316261 0.85 CYP1A2 (0.68) CYP1A2PLAUCTDSP1ALDH1A1CYP3A4
1-Naphthol SCHEMBL27861388 0.84 CYP1A2 (0.74) CYP1A2PLAUCTDSP1ALDH1A1CYP3A4
1-Naphthol SCHEMBL9403268 0.80 ALDH1A1 (0.74) CYP1A2PLAUCTDSP1ALDH1A1CYP3A4
1-Naphthol SCHEMBL3416 0.79 CYP1A2 (1.00) CYP1A2PLAUCTDSP1ALDH1A1CYP3A4
1-Naphthol SCHEMBL29767730 0.79 CYP1A2 (1.00) CYP1A2PLAUCTDSP1ALDH1A1CYP3A4
1-Naphthol SCHEMBL10486461 0.79 CYP1A2 (1.00) CYP1A2PLAUCTDSP1ALDH1A1CYP3A4
1-Naphthol SCHEMBL273260 0.79 CYP1A2 (1.00) CYP1A2PLAUCTDSP1ALDH1A1CYP3A4
1-Naphthol SCHEMBL8417903 0.79 CYP1A2 (0.71) CYP1A2PLAUCTDSP1ALDH1A1CYP3A4
1-Naphthol SCHEMBL29209223 0.78 CYP1A2 (0.85) CYP1A2PLAUCTDSP1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103480285-B A kind of enhancing polysulfone nano-fiber air filter membrane and electrostatic spinning preparation method thereof DONGHUA UNIVERSITY (CN) 2015-10-21 CN claimed
CN-103480285-A Strengthened polysulfone nano-fiber air filter membrane and electrostatic spinning preparation method thereof UNIV DONGHUA 2014-01-01 CN claimed
CN-102561037-B Benzoxazine-modified super-hydrophobic nano fiber membrane and preparation method thereof UNIV DONGHUA 2013-08-07 CN claimed
CN-103225132-A Bioactive carbon fiber preparation method Jiangsu zhuxi active carbon co ltd 2013-07-31 CN claimed
CN-103225133-A Active carbon fiber and preparation method thereof Jiangsu zhuxi active carbon co ltd 2013-07-31 CN claimed
CN-102677193-A Preparation method of phenolic resin matrix nano activated carbon fiber material UNIV DONGHUA 2012-09-19 CN claimed
CN-102653891-A Method for preparing magnetic benzoxazinyl carbon nanofiber material UNIV DONGHUA 2012-09-05 CN claimed
CN-102561037-A Benzoxazine-modified super-hydrophobic nano fiber membrane and preparation method thereof UNIV DONGHUA 2012-07-11 CN claimed
CN-103480285-B A kind of enhancing polysulfone nano-fiber air filter membrane and electrostatic spinning preparation method thereof DONGHUA UNIVERSITY (CN) 2015-10-21 CN disclosed
CN-103480285-A Strengthened polysulfone nano-fiber air filter membrane and electrostatic spinning preparation method thereof UNIV DONGHUA 2014-01-01 CN disclosed
CN-102561037-B Benzoxazine-modified super-hydrophobic nano fiber membrane and preparation method thereof UNIV DONGHUA 2013-08-07 CN disclosed
CN-103225132-A Bioactive carbon fiber preparation method Jiangsu zhuxi active carbon co ltd 2013-07-31 CN disclosed
CN-103225133-A Active carbon fiber and preparation method thereof Jiangsu zhuxi active carbon co ltd 2013-07-31 CN disclosed
CN-102677193-A Preparation method of phenolic resin matrix nano activated carbon fiber material UNIV DONGHUA 2012-09-19 CN disclosed
CN-102653891-A Method for preparing magnetic benzoxazinyl carbon nanofiber material UNIV DONGHUA 2012-09-05 CN disclosed
CN-102561037-A Benzoxazine-modified super-hydrophobic nano fiber membrane and preparation method thereof UNIV DONGHUA 2012-07-11 CN disclosed