Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 11/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28003109 | 1.00 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL28034927 | 1.00 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL19263928 | 0.91 | CES2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL6934192 | 0.82 | EPHX2 (0.36) | EPHX2ADORA3GRM1MAPK8MAPK10 | |
| SCHEMBL1979948 | 0.82 | LMNA (0.43) | EPHX2ADORA3GRM1MAPK8MAPK10 | |
| SCHEMBL2444574 | 0.82 | LMNA (0.43) | EPHX2ADORA3GRM1MAPK8MAPK10 | |
| SCHEMBL322695 | 0.82 | LMNA (0.43) | EPHX2ADORA3GRM1MAPK8MAPK10 | |
| SCHEMBL19935367 | 0.82 | GRM1 (0.36) | EPHX2ADORA3GRM1MAPK8MAPK10 | |
| SCHEMBL10205807 | 0.82 | GRM1 (0.36) | EPHX2ADORA3GRM1MAPK8MAPK10 | |
| Bicarbonate SCHEMBL9845632 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103025725-B | Heterocyclic compounds | ASTELLAS PHARMA INC. (JP) | 2015-09-16 | — | — | CN | disclosed |