Propene

Propene

SCHEMBL28035284

C=C(C)C(=O)O[SiH2]OCCCCC.C=CC

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.51
CES2 O00748 1/20 0.35
HPGD P15428 1/20 0.35
THRB P10828 1/20 0.34
PLA2G2C Q5R387 1/20 0.33
HCAR2 Q8TDS4 2/20 0.33
NAAA Q02083 1/20 0.33
ALDH1A1 P00352 2/20 0.32
EPHX1 P07099 1/20 0.31
LMNA P02545 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HTT P42858 1/20 0.31
HTR2C P28335 1/20 0.30
ZDHHC20 Q5W0Z9 2/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8846409 0.94 TSHR (0.58) TSHRCES2THRBHCAR2NAAA
SCHEMBL3345172 0.89 TSHR (0.50) TSHRCES2HPGDTHRBHCAR2
Propene SCHEMBL28098866 0.77 TSHR (0.86) TSHRCES2HPGDTHRBHCAR2
SCHEMBL14938406 0.76 ALDH1A1 (0.45) TSHRCES2HCAR2NAAAALDH1A1
SCHEMBL29151765 0.74 THRB (0.44) TSHRTHRBALDH1A1LMNA
Propene SCHEMBL28225040 0.73 TSHR (0.67) TSHRCES2HPGDTHRBPLA2G2C
Propene SCHEMBL6374103 0.73 TSHR (0.72) TSHRHPGDTHRBHCAR2NAAA
SCHEMBL27979961 0.72 TSHR (0.61) TSHRCES2HPGDTHRBHCAR2
SCHEMBL7636566 0.72 TSHR (0.56) TSHRTHRBALDH1A1HTT
Propene SCHEMBL27904655 0.71 TSHR (0.40) TSHRHPGDALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104892661-A Propylene acyloxy methacryloxy silane and preparation method of its derivative UNIV SHANDONG 2015-09-09 CN disclosed
CN-104892661-A Propylene acyloxy methacryloxy silane and preparation method of its derivative UNIV SHANDONG 2015-09-09 CN disclosed