Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345172 | 0.95 | TSHR (0.50) | TSHRCES2THRBALDH1A1HCAR2 | |
| Propene SCHEMBL28035284 | 0.94 | TSHR (0.51) | TSHRCES2THRBNAAAALDH1A1 | |
| SCHEMBL14938406 | 0.81 | ALDH1A1 (0.45) | TSHRCES2NAAAALDH1A1EPHX1 | |
| SCHEMBL29151765 | 0.79 | THRB (0.44) | TSHRTHRBALDH1A1 | |
| SCHEMBL27979961 | 0.77 | TSHR (0.61) | TSHRCES2THRBNAAAALDH1A1 | |
| SCHEMBL7636566 | 0.77 | TSHR (0.56) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL7640389 | 0.76 | TSHR (0.59) | TSHRTHRBNAAAALDH1A1POLB | |
| SCHEMBL6551933 | 0.75 | ALDH1A1 (0.52) | TSHRCES2NAAAALDH1A1HCAR2 | |
| SCHEMBL36680 | 0.75 | TSHR (0.96) | TSHRCES2THRBNAAAALDH1A1 | |
| SCHEMBL8846404 | 0.74 | TSHR (0.52) | TSHRCES2THRBNAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780438-A2 | Moulding compositions from polycarbonates | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-25 | — | — | EP | disclosed |