SCHEMBL3345172

SCHEMBL3345172

C=C(C)C(=O)O[SiH2]OCCCC

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
ALDH1A1 P00352 3/20 0.41
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.36
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
CES2 O00748 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
ESR1 P03372 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8846409 0.95 TSHR (0.58) TSHRALDH1A1THRBTDP1POLB
Propene SCHEMBL28035284 0.89 TSHR (0.51) TSHRALDH1A1THRBHPGDHTT
SCHEMBL27979961 0.82 TSHR (0.61) TSHRALDH1A1THRBHPGDATM
SCHEMBL6551933 0.80 ALDH1A1 (0.52) TSHRALDH1A1HPGDATMTDP1
SCHEMBL29151765 0.80 THRB (0.44) TSHRALDH1A1THRB
SCHEMBL30558755 0.76 TSHR (0.57) TSHRALDH1A1THRBHPGDATM
SCHEMBL7636566 0.75 TSHR (0.56) TSHRALDH1A1THRBTDP1POLB
SCHEMBL7638443 0.75 TSHR (0.51) TSHRALDH1A1THRBTDP1POLB
SCHEMBL261665 0.75 ALDH1A1 (0.52) TSHRALDH1A1THRBTDP1
SCHEMBL14938406 0.75 ALDH1A1 (0.45) TSHRALDH1A1CES2HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112912540-B barrier film 株式会社LG化学 2023-08-29 CN disclosed
CN-112912539-B Barrier film 株式会社LG化学 2023-08-08 CN disclosed
CN-112912541-B Barrier film 株式会社LG化学 2023-05-12 CN disclosed
US-20100150610-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-06-17 US disclosed