SCHEMBL28035360

SCHEMBL28035360

OCCN1CCN(Cc2ccccc2)C1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.61
MC4R P32245 1/20 0.56
PKM P14618 1/20 0.53
HTR6 P50406 1/20 0.51
DRD4 P21917 2/20 0.50
CCR3 P51677 1/20 0.50
LMNA P02545 1/20 0.50
POLB P06746 1/20 0.50
TSHR P16473 1/20 0.49
PHGDH O43175 1/20 0.49
MGLL Q99685 1/20 0.49
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 1/20 0.47
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1268041 0.98 SIGMAR1 (0.59) SIGMAR1MC4RPKMHTR6DRD4
SCHEMBL11347486 0.89 SIGMAR1 (0.72) SIGMAR1MC4RPKMDRD4CCR3
SCHEMBL3037947 0.89 SIGMAR1 (0.72) SIGMAR1MC4RPKMDRD4CCR3
SCHEMBL301699 0.86 SIGMAR1 (0.81) SIGMAR1MC4RDRD4CCR3LMNA
SCHEMBL15689951 0.83 CCR3 (0.66) SIGMAR1MC4RDRD4CCR3LMNA
SCHEMBL24023496 0.79 CHKA (0.62) SIGMAR1MC4RPKMCCR3LMNA
SCHEMBL10868742 0.78 MC4R (0.57) SIGMAR1MC4RPKMCCR3LMNA
SCHEMBL11053834 0.78 SIGMAR1 (0.67) SIGMAR1MC4RDRD4LMNAPOLB
SCHEMBL6583768 0.78 CCR3 (0.69) SIGMAR1MC4RDRD4CCR3LMNA
Methane SCHEMBL23120579 0.77 MC4R (0.56) SIGMAR1MC4RCCR3LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105008396-A Peptides that stimulate subcutaneous adipogenesis UNIV CALIFORNIA 2015-10-28 CN disclosed