Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | BACE1 | P56817 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 2/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.56 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235987 | 0.88 | BACE1 (0.60) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL3571475 | 0.88 | BACE1 (0.60) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL3572811 | 0.88 | BACE1 (0.60) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL28036112 | 0.88 | RAB9A (0.61) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL3581359 | 0.86 | LMNA (0.60) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL5175891 | 0.86 | BACE1 (0.58) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL28499154 | 0.85 | ALDH1A1 (0.69) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL5177697 | 0.85 | BACE1 (0.57) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL3569054 | 0.85 | BACE1 (0.57) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL3578662 | 0.84 | BACE1 (0.56) | MEN1MAPTKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415185-A1 | 4-Alkoxy- and 4-(substituted)amino-3-arylpyrrolinones derivatives | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |