Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15528455 | 0.78 | MAPT (0.39) | ALDH1A1ATMKMT2ACRHBPCRHR2 | |
| SCHEMBL21247872 | 0.77 | ALDH1A1 (0.67) | ALDH1A1ATMKMT2ACRHBPCRHR2 | |
| SCHEMBL4279593 | 0.74 | HDAC4 (0.43) | ALDH1A1NPSR1 | |
| SCHEMBL25214800 | 0.74 | ALDH1A1 (0.41) | ALDH1A1ATMKMT2ACRHBPCRHR2 | |
| SCHEMBL9273631 | 0.74 | MAPT (0.52) | ALDH1A1ATMKMT2ACRHBPCRHR2 | |
| SCHEMBL9273639 | 0.74 | MAPT (0.52) | ALDH1A1ATMKMT2ACRHBPCRHR2 | |
| SCHEMBL23923878 | 0.73 | ALDH1A1 (0.53) | ALDH1A1ATMKMT2ACRHBPCRHR2 | |
| SCHEMBL1081803 | 0.72 | NPSR1 (0.41) | ALDH1A1ATMKMT2AMEN1L3MBTL1 | |
| SCHEMBL19778 | 0.72 | NPSR1 (0.70) | ALDH1A1ATMKMT2AMEN1L3MBTL1 | |
| SCHEMBL1099100 | 0.72 | RAB9A (0.45) | ALDH1A1KMT2AMEN1L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153119-A | Pyridylpyrimidyl amine compounds or pyridylpyridyl amine compounds and application thereof | GUANGZHOU KEQIN NEW MEDICINE DESIGN CO LTD | 2015-12-16 | — | — | CN | disclosed |